ABSTRACT
UNLABELLED: The authors present a case of a granular cell tumor of the second digit that was treated with a partial digit amputation. A 49-year-old male presented with an atypical hyperkeratotic lesion at the distal aspect of the second toe with adjacent dystrophy of the nail plate. Radiographs, magnetic resonance images, and, finally, ultrasound images were used to confirm the presence of an underlying mass, and biopsy confirmed the diagnosis of granular cell tumor. Partial digital amputation was eventually undertaken. We feel that it is important for surgeons to maintain a high index of suspicion, particularly when a seemingly benign lesion, such as a hyperkeratosis, fails to respond as expected to treatment. LEVEL OF CLINICAL EVIDENCE: 4.
Subject(s)
Granular Cell Tumor/pathology , Soft Tissue Neoplasms/pathology , Toes/pathology , Amputation, Surgical , Granular Cell Tumor/surgery , Humans , Keratoderma, Palmoplantar/etiology , Male , Middle Aged , Soft Tissue Neoplasms/surgery , Toes/surgeryABSTRACT
The purposes of this study were to develop an instrument to assess the validity of randomized controlled trials and to report on the differences in the validity of randomized controlled trials between two podiatric medical journals and a mainstream medical journal. The study demonstrated that after adequate training, there can be agreement among reviewers evaluating the quality of published randomized controlled trials using an established instrument and guidelines. The results of the study indicate that randomized controlled trials published in podiatric medical journals are less credible than those published in a mainstream medical journal.
