[2 early case reports of adrenogenital syndrome. (Bevern and Romhild (1802)--Telesius (1803))]. / Zwei frühe Fallbeschreibungen des adrenogenitalen Syndroms. (Bevern und Romhild (1802)--Tilesius (1803)).

A number of studies in the history of endocrinology makes reference to two pediatric cases from the early 19th century which are commonly seen as containing the earliest descriptions of the adrenogenital syndrome substantiated by post-mortem findings. Their authors, in addition to being considered the first to furnish an exact description of the symptoms involved, are also occasionally credited with having been aware of the underlying causes of this disorder, i.e. the interaction between the adrenal cortex and the genitalia. The present study demonstrates that this opinion is not founded on facts. Furthermore, a retrospective analysis of the pathological details seemingly irreconcilable with this condition may in fact be explained as resulting from imperfect embryonic development.