ABSTRACT
About a two years later after the reactor accident in Chernobyl we carried out a three-year cytogenetical study of children, dwelling in two regions of Ukraine where the radiation fallout occurred. Chromosome analyses of these individuals have shown a significant increase of the frequency of aberrant cells and chromosomal type aberrations in comparison to the control. We have discovered the increase of the level of chromosomal type aberrations, extension in spectrum of complicate aberrations of chromosome (dicentrics, rings and exchange aberrations) with the years and the increase with the years a share of children with various chromosomal abnormalities. Analyses of sister chromatid exchanges (SCE) and a replication index (RI) show a significant increase of RI meaning with the years in comparison to the control. The SCE frequency didn't altered as compared to the control during different years of investigation.
Subject(s)
Air Pollution, Radioactive/adverse effects , Chromosome Aberrations , Sister Chromatid Exchange/radiation effects , Accidents, Occupational , Child , Humans , Metaphase/radiation effects , Moscow , Nuclear Reactors , Power Plants , Rural Population , Time Factors , Ukraine , Urban PopulationSubject(s)
Environmental Health , Public Health , Child , Humans , Methods , Population Surveillance , USSRSubject(s)
Blood Pressure/radiation effects , Body Temperature/radiation effects , Diathermy , Electromagnetic Fields , Electromagnetic Phenomena , Hand/innervation , Radio Waves , Respiratory Tract Diseases/therapy , Sensation/radiation effects , Adolescent , Blood Pressure/physiology , Body Temperature/physiology , Child , Functional Laterality , Hand/blood supply , Humans , Respiratory Tract Diseases/physiopathology , Sensation/physiologyABSTRACT
The study was undertaken to determine the main laws of setting-up an epidemiological chain "functional state--predisease--disease" and to define causal and effective relation-ships in the system "environment--community health".
