Subject(s)
Anesthesia, Spinal , Meperidine , Adult , Aged , Anesthesia Recovery Period , Clinical Trials as Topic , Female , Humans , Intraoperative Care , Male , Middle Aged , Preanesthetic MedicationSubject(s)
Atracurium/therapeutic use , Cesarean Section , Acid-Base Equilibrium/drug effects , Androstane-3,17-diol/analogs & derivatives , Androstane-3,17-diol/therapeutic use , Anesthesia, Obstetrical , Carbon Dioxide/blood , Drug Evaluation , Female , Fetal Blood/analysis , Fetal Blood/drug effects , Humans , Infant, Newborn , Muscle Relaxants, Central/therapeutic use , Oxygen/blood , Pipecuronium , Piperazines/therapeutic use , PregnancySubject(s)
Androstane-3,17-diol/therapeutic use , Androstanols/therapeutic use , Cesarean Section , Genital Diseases, Female/surgery , Muscle Relaxants, Central/therapeutic use , Piperazines/therapeutic use , Acid-Base Equilibrium/drug effects , Adult , Androstane-3,17-diol/analogs & derivatives , Cholinesterases/blood , Drug Evaluation , Electromyography , Female , Genital Diseases, Female/physiopathology , Hemodynamics/drug effects , Humans , Infant, Newborn , Middle Aged , Pipecuronium , PregnancySubject(s)
Androstane-3,17-diol , Androstanols , Neuromuscular Nondepolarizing Agents , Piperazines , Androstane-3,17-diol/analogs & derivatives , Androstane-3,17-diol/pharmacology , Androstanols/analogs & derivatives , Androstanols/pharmacology , Cholinesterases/blood , Clinical Trials as Topic , Electromyography , Humans , Neuroleptanalgesia , Neuromuscular Junction/drug effects , Neuromuscular Nondepolarizing Agents/pharmacology , Pipecuronium , Piperazines/pharmacology , Synaptic Transmission/drug effectsSubject(s)
Abdomen/surgery , Anesthesia, Intravenous/methods , Etomidate , Fentanyl , Imidazoles , Adult , Aged , Clinical Trials as Topic , Drug Therapy, Combination , Female , Humans , Infusions, Parenteral , Male , Middle Aged , Time FactorsSubject(s)
Anesthesia , Immunity/drug effects , Anesthesia/adverse effects , Anesthetics/immunology , Antibody-Dependent Cell Cytotoxicity/drug effects , B-Lymphocytes/drug effects , Complement System Proteins/immunology , Humans , Immunity, Cellular/drug effects , Immunity, Innate/drug effects , Lymphocyte Activation/drug effects , Macrophages/drug effects , Postoperative Complications/etiology , Surgical Procedures, Operative , T-Lymphocytes/drug effectsABSTRACT
The paper presents the author's experience in post-anesthetic decurarization with a new antagonist of competitive curare. Presented for the first time in 1970, 4-amino-pyridine was found o tbe a substance with a different mode of action than that of reversible inhibitors of cholinesterase, without parasympaticomimetic effects, and without untoward effects on the cardio-circulatory function. It also has a central analeptic effect. This is why the authors consider the new drug as a powerful means for reversing the competitive neuromuscular blockage.
Subject(s)
Aminopyridines/administration & dosage , Central Nervous System Stimulants/therapeutic use , Cholinesterase Inhibitors/administration & dosage , Neuromuscular Depolarizing Agents/administration & dosage , Postoperative Care , 4-Aminopyridine , Curare/antagonists & inhibitors , HumansSubject(s)
Anesthesia, Obstetrical/methods , Electric Stimulation Therapy/methods , Labor, Obstetric , Acid-Base Equilibrium , Adolescent , Adult , Apgar Score , Blood Pressure , Female , Humans , Infant, Newborn , Pregnancy , Pulse , Respiration , Time FactorsABSTRACT
The clinical course of monoanesthesia using ST 1341 (Altezin) preparation during endovesical manipulations and transurethral operative interventions in urology is outlined. The observations are done in a series of 31 patients with systematic study of a number of changes in respiration and hemodynamics, and of their mental and physical state prior to anesthesia and in the period just after awakening. The technique of intravenous Altezin administration does not require special anesthesiologic apparatus. The increase in arterial pressure in the course of anesthesia is accompanied by speeding up of the pulse rate, which should be mandatorily monitored in hypertension patients. Changes in respiration are minimal and transitory. The quick recovery of consciousness and the lack of distressing feelings warrant to consider Altezin monoanesthesia as one of the methods of choice in endovesical urological practice.