[OBESITY AND GYNECOLOGICAL CANCER].

An analysis of 329 patients with gynecological cancer, 120 of them were without obesity and 209 of them were with obesity. Only 36.47% of the cases were with normal weight. There is a trend of increasing obesity with age, with a peak in the age group 60-69 years. The distribution of patients according to BMI and stage of the disease there is a downward trend in the obesity with increasing stage. In both groups of patients (with and without obesity), the volume and type of surgery were carried out depending on the type of tumor process (localization) and stage of the disease. Radical histerectomy with pelvic lymph node dissection (with or without omentectomy) is carried out in 141 patients, of which only 6 were of normal weight, and 135 patients (95.7%) were of different stage of obesity. Total hysterectomy with pelvic lymph node dissection (with or without omentectomy) is carried out in 123 patients, of which only 2 were of normal weight, and 121 patients (98.4%) were of different stage of obesity. Our results show that the volume of surgery in patients with gynecological cancer does not depend the obesity and depend the stage of disease.

[Prognostic factors and the risk of axillary metastases in early breast cancer]. / Prognostichni faktori i risk ot aksilarni metastazi pri ranen rak na mlechnata zhleza.

The authors analyzed the clinical and pathomorphological of T tumors for their association with the likelihood of axillary metastases. Two hundred forty three patients with early breast cancer (T1N0M0 T1N1M0) were studied. All underwent complete lymph node dissection. The parameters of the primary tumor evaluated included size, histologic subtype, hystological grade, hormone receptor status, lymphatic/vascular invasion (LVI). Clinical parameters were age, menopausal status and clinical lymph node status. Sixty two (25.5%) on 243 axillary dissection contained metastases. Univariate analysis showed that nodal involvement were associated with tumors larger than 1 cm and presence of LVI. Decision for complete axillary dissection should be individualized based on prognostic factors for lymph node involvement.