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Folia Med (Plovdiv) ; 61(4): 650-654, 2019 12 31.
Article in English | MEDLINE | ID: mdl-32337877

ABSTRACT

BACKGROUND: Cardiopulmonary bypass in cardiac surgery produces systemic inflammatory response and catabolic state. Severe stress frequently causes abnormalities in thyroid hormones in the absence of primary thyroid disease, defined as sick euthyroid syndrome (SES). MATERIALS AND METHODS: Supplementation therapy with thyroid and anabolic hormones in combination with an adequate nutritional support has been used to improve outcome in critically ill patient after cardiac surgery. RESULTS: Administration of thyroid and anabolic hormones significantly improved patient's condition. CONCLUSIONS: Supplementation therapy with thyroid and anabolic hormones in combination with an adequate nutritional support could be used to improve hemodynamics, achieve transition to anabolic metabolism and enhance recovery, which could eventually help for a reduction in post-operative morbidity and mortality.


Subject(s)
Cardiac Surgical Procedures/adverse effects , Euthyroid Sick Syndromes/drug therapy , Testosterone/therapeutic use , Thyroxine/therapeutic use , Aged , Aorta/surgery , Aortic Aneurysm/surgery , Female , Hormone Replacement Therapy , Humans , Testosterone/blood , Thyroxine/blood
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