[Intensive care for severe acute pneumonia using hemodynamic pulmonary circulatory unloading].

Pulmonary hypertension (PH) and its direct sequel, namely progressive arterial hypoxemia, is one of the severe complications of acute severe pneumonia (ASP). The paper presents the view of the pathogenesis of PH in patients with ASP and discusses a treatment for this complication. Based on the results of their own studies, the authors propose one of the effective methods for decreasing pulmonary vascular resistance. This method is based on the vasoconstrictor concept of the pathogenesis of PH in PH and includes therapy with nitrates. The authors propose to use drugs ameliorating pulmonary arterial hypertension, particularly intravenous nitrates in a dose of 0.2-0.3 mg/kg/day, as a part of intensive care.

[Nitrogen metabolism in elderly persons on a low-calorie diet]. / Sostoianie azotistogo obmena u lits pozhilogo vozrasta, poluchavshikh redutsirovannuiu po kaloriinosti dietu.

The clinical trials covered 9 men aged 58-73 years with daily energy losses of 2200-2350 kcal and given for 10 days the diet (1128 kcal/day) containing different food ingredients. A study was made of the main parameters of nitrogenous metabolism. During the time of being kept on a low-caloric diet, the test subjects lost 2.1 kg body mass. Excretion of total nitrogen dropped 34%, urea 57%. Excretion of creatinine appreciably rose (208% of the initial). The calculation of nitrogenous balance demonstrated protein deficiency to be equal to 209 g during experiments. The concentration of free amino acids in blood plasma decreased: that of replaceable by 29.5%, that of essential ones by 37.6%. It is assumed that the tension of body metabolism affected protein synthesis, whereas the protein quota in the diet did not appear sufficient for elderly subjects.