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1.
Sensors (Basel) ; 23(15)2023 Aug 02.
Article in English | MEDLINE | ID: mdl-37571649

ABSTRACT

In mobile applications such as geomagnetic surveying, two major effects hamper the use of optically pumped magnetometers: dead zones, sensor orientations where the sensors signal amplitude drops; and heading errors, a dependence of the measured magnetic field value on the sensor orientation. We present a concept for an omnidirectional magnetometer to overcome both of these effects. The sensor uses two cesium vapor cells, interrogated by circularly-polarized amplitude-modulated laser light split into two beams propagating perpendicular to each other. This configuration is experimentally investigated using a setup wherein the laser beam and magnetic field direction can be freely adjusted relative to each other within a magnetically shielded environment. We demonstrate that a dead-zone-free magnetometer can be realized with nearly isotropic magnetic-field sensitivity. While in the current configuration we observe heading errors emerging from light shifts and shifts due to the nonlinear Zeeman effect, we introduce a straightforward approach to suppress these systematic effects in an advanced sensor realization.

2.
J Nucl Med ; 59(12): 1901-1906, 2018 12.
Article in English | MEDLINE | ID: mdl-29934406

ABSTRACT

In ovo studies are a valuable option in preclinical research, but imaging studies are severely limited by the costs of dedicated equipment needed for small-sized eggs. We sought to verify the feasibility of using larger, ostrich, eggs (Struthio camelus) for imaging on the PET/CT scanners used for routine clinical investigations. Methods: Ostrich eggs were incubated until shortly before hatching, prepared for intravitelline venous injection of contrast medium or radiotracer, and imaged using native CT, contrast-enhanced CT, and PET/CT. Any technical adaptations that were needed to improve the outcome were noted. Results: Of the 34 eggs initially incubated, 12 became fully available for imaging of embryonal development. In ovo imaging with conventional PET/CT not only was feasible but also provided images of good quality, including on dynamic PET imaging. Conclusion: In ovo imaging with ostrich eggs and routine clinical scanners may allow broader application of this field of preclinical research, obviating costly dedicated equipment and reducing the number of animals needed for classic animal research. Further experiments are warranted to refine this novel approach, especially to reduce motion artifacts and improve monitoring of viability.


Subject(s)
Embryo, Nonmammalian/diagnostic imaging , Embryonic Development , Struthioniformes/embryology , Animals , Contrast Media/administration & dosage , Female , Fluorine Radioisotopes/administration & dosage , Fluorodeoxyglucose F18/administration & dosage , Imaging, Three-Dimensional/methods , Imaging, Three-Dimensional/veterinary , Iodine Radioisotopes/administration & dosage , Ovum/growth & development , Positron Emission Tomography Computed Tomography/methods , Positron Emission Tomography Computed Tomography/veterinary , Radiopharmaceuticals/administration & dosage , Tomography, X-Ray Computed/methods , Tomography, X-Ray Computed/veterinary
3.
Sensors (Basel) ; 17(3)2017 Mar 10.
Article in English | MEDLINE | ID: mdl-28287414

ABSTRACT

We present an optically pumped magnetometer working in a new operational mode-the light-shift dispersed Mz (LSD-Mz) mode. It is realized combining various features; (1) high power off-resonant optical pumping; (2) Mz configuration, where pumping light and magnetic field of interest are oriented parallel to each other; (3) use of small alkali metal vapor cells of identical properties in integrated array structures, where two such cells are pumped by circularly polarized light of opposite helicity; and (4) subtraction of the Mz signals of these two cells. The LSD-Mz magnetometer's performance depends on the inherent and very complex interplay of input parameters. In order to find the configuration of optimal magnetometer resolution, a sensitivity analysis of the input parameters by means of Latin Hypercube Sampling was carried out. The resulting datasets of the multi-dimensional parameter space exploration were assessed by a subsequent physically reasonable interpretation. Finally, the best shot-noise limited magnetic field resolution was determined within that parameter space. As the result, using two 50 mm3 integrated vapor cells a magnetic field resolution below 10 fT/√Hz at Earth's magnetic field strength is possible.

4.
Opt Express ; 20(27): 28683-97, 2012 Dec 17.
Article in English | MEDLINE | ID: mdl-23263106

ABSTRACT

We propose an efficient multiplexing technique for superconducting nanowire single-photon detectors based on an orthogonal detector bias switching method enabling the extraction of the average count rate of a set of detectors by one readout line. We implemented a system prototype where the SNSPDs are connected to an integrated cryogenic readout and a pulse merger system based on rapid single flux quantum (RSFQ) electronics. We discuss the general scalability of this concept, analyze the environmental requirements which define the resolvability and the accuracy and demonstrate the feasibility of this approach with experimental results for a SNSPD array with four pixels.


Subject(s)
Conductometry/instrumentation , Electronics/instrumentation , Photometry/instrumentation , Signal Processing, Computer-Assisted/instrumentation , Electric Conductivity , Equipment Design , Equipment Failure Analysis , Light , Photons
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