ABSTRACT
This is an update on the treatment of anaphylactic shock in pregnant women. Most guidelines recommend adrenaline as first-line treatment in all patients, but in pregnant patients some recommend ephedrine due to a potential risk of utero-placental hypoperfusion with adrenaline. However, ephedrine is a less potent vasopressor than adrenaline and does not possess the same anti-inflammatory or broncho-dilating effects. As immediate and correct treatment is essential for both the maternal and the fetal outcome, adrenaline should be first-line treatment also in pregnant women.
Subject(s)
Anaphylaxis/drug therapy , Ephedrine/therapeutic use , Epinephrine/therapeutic use , Pregnancy Complications/drug therapy , Vasoconstrictor Agents/therapeutic use , Algorithms , Anaphylaxis/diagnosis , Diagnosis, Differential , Ephedrine/pharmacology , Epinephrine/adverse effects , Epinephrine/pharmacology , Female , Humans , Placenta/blood supply , Pregnancy , Risk Factors , Uterus/blood supply , Vasoconstrictor Agents/adverse effects , Vasoconstrictor Agents/pharmacologyABSTRACT
We describe a case report of a 23-year-old man with acute pharyngeal injuries due to frostbite subsequent to inhalation of propane. He was fiber-optically intubated on admission to hospital since his airways were considered acutely compromised. He was subsequently kept intubated for 11 days due to persistent pharyngeal oedema and frostbite injuries. The latter is caused by low temperature of propane upon release from a pressurized container. Injuries caused by frostbite often gradually progress and thus caution should be exerted in regards to airway management.
