[Heparin-free hemodialysis in chronic patients for temporary management of conditions with a high risk of bleeding]. / Heparinfreie Hämodialyse bei chronischen Patienten zur kurzfristigen Uberbrückung von Situationen mit starker Blutungsgefahr.

It was reported on 30 heparin-free hemodialyses in 7 chronic patients by means of the capillary dialyzer MLW Typ II. The procedure is described in detail. It is used in the case of threatening bleeding complications along with absence of bed-sided coagulation tests. The additional expense is justifiable, the procedure is effective and well-tolerable.

[Need for transfusion in urea-oriented and temporally individualized dialysis planning in comparison with dialysis with standard time intervals]. / Transfusionsbedarf bei harnstofforientierter und zeitlich individualisierter Dialyseführung im Vergleich zur Standardzeitdialyse.

From january 1984 to july 1986 three patient groups were investigated. With regard to the frequency of transfusion per month, the pre-dialysis urea profile, the use of heparin and the clinical rehabilitation no significant differences were found between the urea-orientated individualized short-term dialysis, the urea-orientated standard-time dialysis and standard dialysis with maximal blood flow through the dialyzer. Therefore, a superior utilization of the dialysis places seems to be possible, but further long-term investigations are necessary.

[Significance of viral hepatitis in a dialysis center for patients and health personnel--a 5-year review]. / Die Bedeutung der Virushepatitis im Dialysezentrum für Patienten und Pflegekräfte--Eine 5-Jahres-Ubersicht.

As a nosocomial infection the virus hepatitis is now as ever of importance in dialysis centres. In a 5-year study (1980-1985) in the dialysis centre of the County Hospital St. Georg Leipzig we found an annual incidence of 14 to 20% in patients and in 25 out of 26 members of the staff signs of an overcome infection could be proved. In these cases above all younger persons with an average age of 31 years were affected about 1.5 years after the beginning of work. For patients the entry into the transplant recipient register retarded by on an average 9.4 months, for patients already registered a transient reincorporation of 12.4 months was the result. Despite the active inoculation against the virus hepatitis B on account of the further existing endangering by the NANB hepatitis and possible inoculation eruptions in the immune-disturbed dialysis patients the observation of a strong hygiene regimen is necessary.

[Urea-oriented dialysis management in routine care]. / Harnstofforientierte Dialyseführung im Routinebetrieb.

An approximation variant of the 1-compartment model and its clinical application in routine work are described. It is demonstrated how quantity and distribution of the dialyses, clearance and duration of the dialysis are to be chosen in order to obtain in a patient a course of the urea concentration striven for. A probable residual dialysis is taken into consideration. By this means an adaptation of the management of dialysis to the protein balance of the patient and to the effect of the dialysis with regard to easily dialysable substances is possible. The system demonstrated stood the test in clinical routine work. It is simple in its application, since the connections can be brought in easily legible graphs. Decisions in practice on duration of the dialysis, type of dialyzer and frequency of dialysis get a quantifiable basis.

[Semi-continuous peritoneal dialysis - an advantageous modification of the peritoneal dialysis technic]. / Semikontinuierliche Peritonealdialyse -- eine vorteilhafte Modifikation der Peritonealdialysetechnik.

Using a single-needle-monitor known from the haemodialysis in the peritoneal dialysis vastly automatized short cycles may be achieved which make possible an increase of effectiveness and thus a shortening of the time of dialysis. Thus patient and personnel are relieved. In the practical use the technique proved to be simple, no known complications conditioned by technique appeared.

[Supplementary data on the outcome of rapid electrochemical methods to determine significant bacteriuria]. / Ergänzende Angaben zum Ablauf der elektrochemischen Schnellmethode zur Erfassung signifikanter Bakteriurien.

After description of the highly effective, cheap and independent of consumption material rapid electrochemical method for the proof of significant bacteriurias the author enters some detail problems which seem worth to be taken into consideration when using this test method. The result is a sensitivity of the method of 92.3% and a specificity of 96.2%. The experimental conditions may still be simplified for screening examinations.

[Systolic time intervals during sequential ultrafiltration and hemodialysis]. / Systolische Zeitintervalle des Herzens bei kontrollierter sequentieller Ultrafiltration und Hämodialyse.

The effects of a forced withdrawal of fluid by ultrafiltration and the influences of a connected haemodialysis on the period of isometric contraction of the heart were recorded by periodical registration during the treatment. A statistically certain decrease of the LVET (-19.2%) and an increase of the PEP (+ 11.1%) were found. Since at least in the period of the isolated ultrafiltration several essential parameters of the interior milieu do not change decisively, as cause for the changes observed of the systolic intervals of the heart period the decrease of the preload is discussed. During the period of ultrafiltration on an average 15.3 +/- 3.3 ml of plasma water were taken per minute.

[A simple method for the prediction of the time of onset of uremia in patients with chronic kidney failure]. / Einfache Methode zur zeitlichen Festlegung des voraussichtlichen Urämieeintrittes bei chronisch Nierenkranken.

Following a method described by Mitch and co-workers in patients with chronic retention of substances normally contained in the urine the reciprocal values of serum creatinine determinations were figured in the long-term course. Of 22 patients 20 showed an extensively linear decrease of 1/creatinine in the period, independently on the fact, whether a pyelonephritis, glomerulonephritis or cystic kidneys were the basis disease. The correlation calculation confirms with a mean correlation coefficient of 0.842 in a dispersion of +/- 0.106 the connection mentioned so that possibilities of the prognosis for the moment of the dialysis and for an objective judgment of the therapeutic success are outlined.

[First results with an electrochemical rapid method for the detection of significant bacteriurias]. / Erste Ergebnisse mit einer elektrochemischen Schnellmethode zur Erfassung signifikanter Bakteriurien.

The measuring oft he pO2-decrease in the urine within 30 min by means of the micro-measuring-chamber MWK-W in connection with the oxygen measuring intensifier M 65 allows a quick orientation about a significant bacteruria. The concordance with the results of the simultaneously performed bacteriological investigation is 90% in 1,036 midstream urine specimens. This electro-chemical method allows: 1. the sufficiently certain orientation about a significant bacteruria, 2. from principle the establishment of all aerobic kinds of germs which play a role in the clinical practice in inflammations of the urinary tract, to investigate, 3. a large number of urine specimens in a short time with a relatively small expenditure: a bacteriological laboratory is not the condition, 4. the performance of larger screening investigations.

[Cardiac function diagnosis in the hemodialysis practice using so-called Rentsch tension index]. / Kardiale Funktionsdiagnostik in der Dialysepraxis mit dem sog. Anspannungsindex nach Rentsch.

The so-called tension index PI after Rentsch allows a frequently repeatable control of the degree of sufficiency of the heart with slight annoyance of the patient and moderate expenditure of time. In dialysis patients in whom the heart stress and the conditions of the interior milieu frequency acutely change with the help of the PI valuable hints for the treatment could be received.