ABSTRACT
OBJECTIVES: The study aimed to estimate the prevalence of depression and anxiety among university students during the peak of COVID19 pandemic in the Slovak Republic in December 2020. The secondary goal was to compare results with a study from 2018 at the same university. METHODS: A web-based cross-sectional study was administered at the Comenius University in Bratislava. The final sample consisted of 1,786 participants (approx. 80 % females) with the mean age and standard deviation of M=21.15 and SD=3.53. An online battery of self-report measures of depression, anxiety, perceived stress, loneliness, and resilience was administered. RESULTS: The prevalence rates of moderately severe tosevere depression and anxiety were 34.3 % and 20.1 %, respectively. Depression and anxiety were associated with younger age, higher perception of stress, higher loneliness, and lower resilience. In comparison with 2018, we found a two-fold increase in depression and anxiety. The increase was present across most of the depression and anxiety symptoms. CONCLUSION: The result of the study revealed elevated rates of depression and anxiety during the second wave of COVID-19 pandemic in Slovakia. Various demographic and psychological factors were associated with more severe depression and anxiety among university students. Some subgroups of students are at the higher risk of mental health problems (Tab. 4, Ref. 26).
Subject(s)
COVID-19 , Pandemics , Anxiety/epidemiology , Cross-Sectional Studies , Depression/epidemiology , Female , Humans , Male , Mental Health , SARS-CoV-2 , Slovakia/epidemiology , Stress, Psychological , StudentsABSTRACT
The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread between dogs by the allogeneic transfer of living cancer cells. The infectious agents in CTVT are the living cancer cells themselves, which are transmitted between dogs during coitus. CTVT first arose several thousand years ago and the disease has a global distribution and is frequently observed in dogs from Brazil. We evaluated the utility of a LINE-MYC quantitative polymerase chain reaction for diagnosis of CTVT cases in Brazil. Our analysis indicated that the LINE-MYC rearrangement was detectable in all CTVT samples but not in their corresponding hosts. This genetic assay proves to be a useful tool for providing a definitive molecular diagnosis of CTVT, which presents with varying degrees of aggressiveness and invasiveness in different host dogs and can therefore be a diagnostic challenge in some specific cases.
Subject(s)
Dog Diseases/diagnosis , Real-Time Polymerase Chain Reaction/veterinary , Venereal Tumors, Veterinary/diagnosis , Animals , Brazil , DNA, Neoplasm/genetics , Dog Diseases/genetics , Dog Diseases/transmission , Dogs , Female , Male , Real-Time Polymerase Chain Reaction/methods , Sensitivity and Specificity , Venereal Tumors, Veterinary/geneticsABSTRACT
The development of antimicrobial resistance in main pathogens of respiratory system infections (S. pneumoniae, H. Influenzae, B. catarrhalis) reduces the range of unprotected penicillins indications. The inhibitors of beta-lactamase rendered back the original spectrum of antimicrobial activity to aminopenicillins and ureidopenicillins, and withheld them within the most frequently used armamentarium of antimicrobial drugs for the therapy of more severe infections. The prescription of penicillins is ruled according to the localization of infection, most frequent pathogens and by the epidemiologic situation. A combined antibiotic therapy is indicated in severe infections. An important indication area is the prophylactic administration of penicillins in recurring tonsilopharyngitis, recurring otitis media and eradication of meningococcal carriership. (Tab. 1, Ref. 3.).
