ABSTRACT
Therapy for pulmonary tuberculosis in patients is complicated by their negative psychoemotional state frequently deteriorated by long inpatient stay. Enhancing the efficiency of rehabilitative measures in phthisiology requires active optimization of the patients' mental state. This problem can be solved by a package of correction measures involving psychological correction with reflex therapeutic normalization of the functional state of the cortical regions of the central nervous system in patients with pulmonary tuberculosis. One hundred tuberculosis patients with decompensated mind, including 60 with OG and 40 with KG, were examined. A noticeable psychoemotional improvement was reliably detected 5 months after complex correction psychological and neuropsychological accompaniments of standard chemotherapy in the OG study.
Subject(s)
Antitubercular Agents/therapeutic use , Emotions/drug effects , Mental Disorders/psychology , Tuberculosis, Pulmonary/drug therapy , Adolescent , Adult , Female , Follow-Up Studies , Humans , Male , Mental Disorders/etiology , Mental Disorders/therapy , Middle Aged , Reflexotherapy/methods , Treatment Outcome , Tuberculosis, Pulmonary/complications , Tuberculosis, Pulmonary/psychology , Young AdultABSTRACT
Medical and psychological studies have established that the personality of a psychosomatic patient has characteristic specific features that determine his emotional reactions and lead to psychological and physiological destructions. Searching for the specificity of psychogenesis of pulmonary tuberculosis may be guided by the V. N. Myasishchev provisions of psychology of relations and should be aimed at analyzing the patients' significant experiences that cause their prolonged affective tension. This paper defines the tasks of studying the psychological and neuropsychological features of patients with pulmonary tuberculosis and specifies an adequate set of psychodiagnostic procedures to solve the put problems. The findings may provide insight into the specific character of psychogenesis of pulmonary tuberculosis and into a relationship of the psychological traits of patients with this nosological entity to the physiological processes at the somatic and cerebral level.
Subject(s)
Psychophysiologic Disorders/diagnosis , Psychophysiologic Disorders/epidemiology , Tuberculosis, Pulmonary/epidemiology , Comorbidity , Humans , Prevalence , Psychophysiologic Disorders/psychology , Russia/epidemiology , Severity of Illness IndexABSTRACT
Wearisome mental stress arising from experiencing aggressive sensations in the subjectively and objectively unbearable situation may be a significant contributor to the development of a psychosomatic disorder. A hundred and twenty patients with new-onset pulmonary tuberculosis underwent a psychological study. The steady-state personality trait in these patients is hostility as overpretentiousness, susceptibility to offence, and suspiciousness. The development of hostility in patients with pulmonary tuberculosis is associated with masterful upbringing in their parental families, which promotes the development of a sense of guilt, sensitivity to their criticism, restrained actions, and inattention. The inclination of these patients to feel themselves attacked victims forces them to mobilize their energy to repulse the aggressive reality as they perceive, maintaining the abnormally high level of affective tension that impairs autonomic balance in the body and makes the treatment of tuberculosis ineffective. It is expedient to take into account the revealed psychological characteristics of patients with pulmonary tuberculosis in the mentally corrective constituent of a therapeutic process in order to achieve the optimal cooperation in the physician-patient-family system.
Subject(s)
Aggression/psychology , Stress, Psychological/psychology , Tuberculosis, Pulmonary/psychology , Adolescent , Adult , Disease Progression , Female , Follow-Up Studies , Humans , Male , Middle Aged , Risk Factors , Stress, Psychological/etiology , Surveys and Questionnaires , Tuberculosis, Pulmonary/complicationsABSTRACT
A virus, identified as cowpox virus by its biological properties and the results of the analysis of its DNA, was isolated from a sick 4-year-old child with a clinical picture of pox, though having had no contacts with known natural carriers of the causative agent of this infection. At the same time the isolated virus was found to differ from the reference strain, as well as from other isolates of vaccinia virus by some biological markers (and in particular by the structure of cytoplasmic inclusions of type A) and by the restriction profile of DNA. The Hind III maps indicating the location of restriction sites made it possible to localize the genome differences established in this study. The specific feature of this case was the previous close contact of the child with a mole which was probably the source of infection.
