[Microbiological profile of postoperative infection in current oncology surgery]. / Mikrobiologicheskii profil' posleoperatsionnoi infektsii v sovremennoi onkokhirurgii.

AIM: To analyze in-hospital infection in oncology center within 2012-2016. MATERIAL AND METHODS: There were 98 patients with nosocomial infection who underwent surgery for malignancies. Microbiological examination of biological materials was carried out by appropriate laboratories according to generally accepted methods. RESULTS: Mono- and polymicrobial infection was observed in 58 and 42% of cases. Staphylococcus aureus was the most common agent in patients with microbial infection. Minimal inhibitory concentration of vancomycin (MIC) ≥1.0 µg/ml was revealed in 60% of microbes. Microbial agents isolated were resistant to antibacterial drugs used to prevent postoperative infectious complications. CONCLUSION: In-hospital infection was accompanied by staphylococci as a rule. Causative agents of nosocomial infections are usually resistant to conventional antibacterial drugs. Moreover, 60.1% of microbes had minimal inhibitory concentration of vancomycin ≥1.0 µg/ml that indicated the need for alternative therapeutic agents.

[Thoracoscopic subtotal esophageal resection for benign esophageal diseases]. / Torakoskopicheskaia subtotal'naia rezektsiia pishchevoda pri ego dobrokachestvennykh zabolevaniiakh.

AIM: To investigate the role of video-assisted subtotal esophageal resection in treatment of patients with benign esophageal diseases. MATERIAL AND METHODS: Fifty-one patients with benign esophageal diseases have undergone subtotal esophageal resection in our department for the period 2010-2017. Thoracoscopic technique was applied in 25 cases, open approach - in 26 patients. Total surgery time, thoracoscopic stage duration, length of hospital-stay (LOS), ICU-stay, Clavien-Dindo morbidity rates with separate registration of respiratory complications, mortality have been considered. RESULTS: Groups were similar in terms of age, gender, ASA status. Thoracoscopic stage duration gradually decreased from 175 to 65 min with average time of 102 (75; 123) min. Total surgery time was 390 (270; 495) min in group 1 and 465 (341; 561) min in the control group (р=0.035). Mean ICU-stay decreased up to 2 (1.25; 3.75) days compared with the control group (5 (3.92; 5.85) days, р<0.0001). Conversion rate was 8%. In the main group complications Clavien-Dindo grade 2 were detected in 10 (40%) patients compared with 20 (69%) cases in the control group (р=0.009). Respiratory complications occurred in 5 patients in group 1 and in 13 cases of the control group (р=0.039). Mortality was absent. CONCLUSION: Thoracoscopic subtotal esophageal resection may be advisable alternative to open surgery for patients with benign esophageal diseases due to lower postoperative morbidity and earlier rehabilitation followed by improved outcomes.