ABSTRACT
A mathematical methodology is suggested which allows the a priori calculation of the risk of premature delivery, by a formula relying on the scores attributed to different specific risk factors (maternal virus infections included). The scores are estimated either directly, or starting from the scores of nonspecific factors. The statistical significance of the different scores, correlations and formulas is analyzed.
Subject(s)
Infant, Premature , Pregnancy Complications , Virus Diseases/complications , Adult , Female , Humans , Infant, Newborn , Obstetric Labor, Premature , Pregnancy , Pregnancy Complications, Infectious , RiskABSTRACT
Various techniques are described for the preparation of complement-fixing(CF) antigen from the cell-associated phase of two strains of human cytomegalovirus. Preliminary results regarding the preparation of CF antigen from extracellular virus are also presented. The qualities and shortcomings of each of the biological preparations obtained by the different procedures are outlined.
Subject(s)
Antigens, Viral/isolation & purification , Cytomegalovirus/immunology , Antigens, Viral/immunology , Cell Line , Complement Fixation Tests , Cytomegalovirus/growth & development , Humans , Hydrogen-Ion Concentration , Temperature , UltrasonicsABSTRACT
Administration of specific antimumps immunoglobulins(Ig) to mumps contacts in various children communities conferred protection only when performed early after the outbreak of the epidemic and if the proportion of previous mumps cases did not surpass 8% of the total number of children. Application of specific Ig to mumps patients within the first 5 days after onset prevented the appearance of secondary determinations and/or complications and reduced the duration of the disease and of the hospitalization period. The efficiency of standard gamma-globulins was very limited.
