ABSTRACT
MATERIAL AND METHOD: We analyzed 362 patients with schizophrenia admitted during 2016 in an acute psychiatric ward and in a chronic psychiatric ward, diagnosed with paranoid or other schizophrenia, according to DSM-IV-TR, which, after remission of the symptoms of the acute episode, they benefited from antipsychotic therapy only in oral formulation. For some of these patients we instituted maintenance therapy with depot formulas. Patients were followed for up to two years. RESULTS: Comparing the level of adherence to therapy, we found a statistically significant improvement, from 42.96% to 76.30%. Although we estimate that adherence to LAI therapy is over 90%, almost a quarter of patients have given up this type of treatment at some point due to side effects. Carrying out the comparative analysis of the number of hospitalizations per year, from the past and from the follow-up period, as well as of the scores registered at the scales used (PANSS, CGI, GAS, WHOQOL), in dynamics, we demonstrated the appearance of statistically significant changes. CONCLUSIONS: the administration of antipsychotic therapy through LAI-type depot formulas can improve the therapeutic adherence of the patient with schizophrenia, thus improving the evolution of the disease and the quality of life.
ABSTRACT
In the present study, we highlight the types of anxiety and the coping strategies employed by the students at the Medicine, Pharmacy and Nursing Faculties, at the same time comparing them with the general population. This research involved 333 first year students, 18-20 years of age. We used the Endler Multidimensional Anxiety Scales-Trait (EMAS-T) and Social Anxiety Scale-Trait (SAS-T) and two coping measuring instruments, Cognitive Emotion Regulation Questionnaire (CERQ) and Strategic Approach to Coping Scale (SACS). We obtained an overview on the hierarchy of the types of anxiogenic situations for the study participants, by gender and specialization. We analyzed and discussed the correlations between anxiety and coping and we discussed the results of the factor analysis. We noticed the students' predilection for maladaptive coping mechanisms and how anxiety relates to their professional choice.
