[Parovarian cysts and tumors in adolescent girls]. / Parovariální cysty a nádory u dospívajících dívek.

Biopsy in 30 girls suffering from parovarial lesions showed 27 parovarial cysts and 3 parovarial tumours. Girls' age varied between 12 and 17--except an 1-year-old infant. 13 girls had to be operated on paramesonephric unilocular usually solitary cysts with a tubal sort of lining. 4 girls had simultaneous paramesonephric and mesonephric cysts which were bilateral in two cases. Pure mesonephric cysts were found in further 9 patients combined with other bioptic lesion; they were microscopical and character of their lining was that of dilated mesonephric ducts. Only one cyst which had to be operated on had mesothelial lining in all sections. Parovarial tumours were bilateral in one patient--a serous papillary cystadenoma followed later by serous cystadenofibroma; other 2 patients had serous cystadenofibroma and borderline serous papillary cystadenoma. Neoplastic nature of the last 3 lesions was not established until the biopsy.

[Hyperandrogenic states in girls and young women]. / Hyperandrogenní stav u dívek a mladých zen.

The authors present a group of 20 girls and young women with various clinical symptoms of hyperandrogenism. The common finding in all these patients is an elevated excretion of desoxy-fraction of 17-oxosteroids, in particular androsterone in urine. The authors describe in detail the case-history of a girl with pubarché praecox and premature closure of the epiphyseal crevices and a young woman with polycystic ovary syndrome. The authors supplement the reflections on the aetiology of hyperandrogenism by suggestion of an algorithm examination and therapeutic procedure when excessive androgen production in the female organism is confirmed.