ABSTRACT
This work presents the results of treatment of 60 patients with 2nd degree hemorrhagic shock at pre-hospital and hospital stages by different variations of infusion therapy. It is established that balanced infusion therapy in patients with 2nd degree hemorrhagic shock helps to stabilize the system hemodynamic and improve the general condition. The balanced infusion therapy does not lead to unfavorable changes in acid-alkaline and electrolyte balance.
Subject(s)
Fluid Therapy/methods , Rehydration Solutions/administration & dosage , Shock, Hemorrhagic/therapy , Adult , Crystalloid Solutions , Gelatin/administration & dosage , Hemodynamics/physiology , Humans , Isotonic Solutions/administration & dosage , Plasma Substitutes/administration & dosage , Severity of Illness Index , Shock, Hemorrhagic/blood , Shock, Hemorrhagic/physiopathology , Succinates/administration & dosage , Treatment Outcome , Water-Electrolyte Balance/physiologyABSTRACT
The comparative analysis of different protocols of infusion therapy of the hemorrhagic shock stage III was performed. The infusion of the colloid solution of hydroxiethylstarch 200/0.5 and non-balanced crystalloid 0.9% solution of natrium chloride leads to the development of negative changes in homeostasis. Whereas infusion of the 4% solution of the modified gelatin and balanced crystalloid solition (sterofundin) allows to avoid the registered changes in electrolyte and alkaline balance.
Subject(s)
Gelatin , Homeostasis/drug effects , Hydroxyethyl Starch Derivatives , Isotonic Solutions , Shock, Hemorrhagic , Sodium Chloride , Adult , Blood Volume/drug effects , Crystalloid Solutions , Emergency Medical Services/methods , Female , Fluid Therapy/methods , Fluid Therapy/standards , Gelatin/administration & dosage , Gelatin/adverse effects , Hemorrhage/complications , Hemorrhage/drug therapy , Hemorrhage/metabolism , Hemorrhage/physiopathology , Humans , Hydroxyethyl Starch Derivatives/administration & dosage , Hydroxyethyl Starch Derivatives/adverse effects , Hypovolemia/drug therapy , Hypovolemia/etiology , Hypovolemia/physiopathology , Infusions, Intravenous , Isotonic Solutions/administration & dosage , Isotonic Solutions/adverse effects , Male , Plasma Substitutes/administration & dosage , Plasma Substitutes/adverse effects , Severity of Illness Index , Shock, Hemorrhagic/drug therapy , Shock, Hemorrhagic/etiology , Shock, Hemorrhagic/metabolism , Shock, Hemorrhagic/physiopathology , Sodium Chloride/administration & dosage , Sodium Chloride/adverse effects , Treatment Outcome , Water-Electrolyte Imbalance/drug therapy , Water-Electrolyte Imbalance/etiology , Water-Electrolyte Imbalance/metabolism , Water-Electrolyte Imbalance/physiopathologyABSTRACT
The authors present a comparative assessment of the efficiency of balanced and unbalanced crystalloid solutions used in the program of infusion therapy in patients with blood loss. It was found that infusion therapy with unbalanced crystalloid solution facilitated the appearance of electrolytic changes and decrease of pH of venous blood while infusion therapy with balanced crystalloid solution did not cause negative changes of the water-electrolytic and acid-base balance.
Subject(s)
Fluid Therapy/methods , Hemorrhage/therapy , Isotonic Solutions/administration & dosage , Acid-Base Equilibrium , Adolescent , Adult , Crystalloid Solutions , Follow-Up Studies , Hemorrhage/metabolism , Humans , Infusions, Intravenous , Middle Aged , Prospective Studies , Rehydration Solutions , Single-Blind Method , Treatment Outcome , Young AdultABSTRACT
One hundred and sixty-two patients operated on organs of lower part of abdominal cavity were studied. All the patients were divided into 3 groups depending on anesthesia method: general, epidural and spinal anesthesia. Efficacy of different methods of intrasurgical anesthesia for prevention of postoperative algetic syndrome and decrease of complications number was compared. It is demonstrated that spinal and epidural anesthesia ensure prophylaxis of postoperative algetic syndrome, but spinal anesthesia is the most simple, safe and cost-effective method.
