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3.
Fiziol Zh SSSR Im I M Sechenova ; 63(12): 1644-52, 1977 Dec.
Article in Russian | MEDLINE | ID: mdl-563809

ABSTRACT

The emotional stress induced in dogs by means of electrodermal stimulation, lowered the blood insulin and increased the corticoids and sugar contents. Bilateral amygdalectomy eliminated the inhibitory effect of the electrodermal stimulation on the insular apparatus and caused a lesser albeit prolonged increase in the blood corticoid content. The blood sugar under these conditions was also somewhat increased. Different effects of separate amygdaloid nuclei on insulin secretion were revealed in acute experiments. The inhibitory effect of amygdaloid nuclei is realised through ventromedial hypothalamic nucleus


Subject(s)
Adrenal Cortex Hormones/metabolism , Amygdala/physiology , Insulin/metabolism , Stress, Psychological/physiology , Adrenal Cortex Hormones/blood , Animals , Blood Glucose/analysis , Cats , Dogs , Electric Stimulation , Electroencephalography , Humans , Hypothalamus/physiology , Insulin/blood , Insulin Secretion , Time Factors
4.
Biull Eksp Biol Med ; 80(12): 3-6, 1975 Dec.
Article in Russian | MEDLINE | ID: mdl-1225394

ABSTRACT

Acute experiments were conducted on adult cats. Injection of insulin microdose (0.025 U/kg with 0.025 ml of saline) into the posterior hypothalamic nucleus caused an increase in the blood sugar level 10 and 70 min after the injection. Changes of the blood sugar level correlated with the EEG activation of the posterior hypothalamic nucleus in response to the insulin injection, spreading to the lateral hypothalamus. However, hormonal stimulation of the posterior hypothalamic nucleus against the background of bilateral coagulation of the lateral hypothalamus produced no increase in the blood sugar level in 10 min. This is indicative of the participation of the lateral hypothalamus in the realization of hyperglycemic reactions in response to the insulin injection into the posterior hypothalamic nucleus.


Subject(s)
Blood Glucose/metabolism , Hypothalamus, Posterior/physiology , Hypothalamus/physiology , Insulin/pharmacology , Animals , Cats , Electroencephalography , Hypothalamus, Posterior/drug effects
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