ABSTRACT
A new method of intragastral disintegration of big blood coagula by mechanical waves is described. Intragastral application of ultrasound was disappointing. A flexural electromagnetic resonator was brought up for clinical trial and showed an effective intragastral thrombotripsy. Even other substances like tablets, food or scybala could be disintegrated. The described method represents a simple, safe and efficient procedure which will enrich the catalogue of possiblities in endoscopic examinations.
Subject(s)
Electromagnetic Phenomena/therapeutic use , Thrombosis/therapy , Ultrasonic Therapy , Vibration/therapeutic use , Gastrointestinal Hemorrhage/therapy , Gastroscopy , HumansABSTRACT
1. A new method of destroying thrombi in blood vessels by ultrasound and simultaneously removing them is reported. 2. Experiments were performed in twenty dogs with artificial thrombi in the iliac and femoral arteries and veins. The length of the thrombi ranged from 4 to 5 cm and the age from 12 h to 10 days. The unit used consisted of a generator, a frequency counter, an ultrasonic transducer with the hollow waveguide and a vacuum pump. For protection of the vessel wall the guide is surrounded by a plastic tube. The ultrasonic frequency is 26-5 kHz, the amplitude 25-30 micronm. The time needed to destroy the thrombus by ultrasound and suck out the thrombotic material ranged from 2-5 to 5 min. 3. To check side effects, experiments were performed in forty-four dogs. No significant changes were seen in the fibrinolytic system or microscopic structure of the vessel wall after ultrasound.
Subject(s)
Thrombosis/therapy , Ultrasonic Therapy , Animals , Dogs , Time FactorsABSTRACT
By ultrasound it is possible to destroy thrombi intravascular and remove them by a hollow flexible probe at the same time. Experiments were now performed in 6 dogs with 2-9 days old thromboses in the femoral or iliac veins, to detect embolisation during ultrasound-thrombolysis. Parameters were pulmonary angiograms and lung scans. Only in one dog with a floating thrombus in the iliac vein signs of pulmonary embolism were found after thrombolysis. The controls of the other 5 dogs were normal.
