1.
Antimicrob Agents Chemother
; 53(2): 814-7, 2009 Feb.
Article
in English
| MEDLINE
| ID: mdl-19015359
ABSTRACT
Synergy time-kill testing of levofloxacin alone and in combination with CHP-105, a representative DnaK inhibitor, against 50 gram-negative rods demonstrated that 34 of the 50 strains tested showed significant synergy between levofloxacin and CHP-105 after 12 h and 24 h. Fourteen of these 34 organisms were quinolone resistant (levofloxacin MICs of > or =4 microg/ml).