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1.
Appl Radiat Isot ; 208: 111297, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38513476

ABSTRACT

Proton therapy has emerged as an advantageous modality for tumor radiotherapy due to its favorable physical and biological properties. However, this therapy generates induced radioactivity through nuclear reactions between the primary beam, secondary particles, and surrounding materials. This study focuses on systematically investigating the induced radioactivity in the gantry room during pencil beam scanning, utilizing both experimental measurements and Monte Carlo simulations. Results indicate that patients are the primary source of induced radioactivity, predominantly producing radionuclides such as 11C, 13N, and 15O. Long-term irradiation primarily generates radionuclides like 22Na, 24Na, and 54Mn etc. Additionally, this study estimates the individual doses received by medical workers in the gantry room, the irradiation dose for patient escorts, and the additional dose to patients from residual radiation. Finally, the study offers recommendations to minimize unnecessary irradiation doses to medical workers, patient escorts, and patients.


Subject(s)
Proton Therapy , Radioactivity , Humans , Proton Therapy/methods , Radiotherapy Dosage , Radioisotopes , Monte Carlo Method , Radiotherapy Planning, Computer-Assisted/methods
2.
Appl Radiat Isot ; 206: 111233, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38340532

ABSTRACT

Carbon ions have unique physical and biological properties that allow for precise targeting of tumors while minimizing damage to surrounding healthy tissues. The emitted neutrons dominate the radiation field in the treatment room and pose challenges for radiological shielding. Concrete is extensively utilized in the construction of radiotherapy facilities due to its good shielding characteristics, and it can be easily poured into the desired shapes and thickness. The difference in composition of concrete affects the characteristics of neutron attenuation and activation performance. Therefore, the purpose of this study is to clarify the shielding properties and activation performances of four types of concrete for carbon ion therapy facilities. The Monte Carlo method is used to analyze the neutron spectra from thick targets upon carbon ion bombardment. Furthermore, the deep attenuation efficiency of the secondary neutron in different compositions of concrete is discussed. The shielding design is developed to ensure compliance with the prescribed dose limit outside the shielding during operation. Finally, the induced radioactivity in concrete is estimated for both short-term and long-term operation. The produced radionuclides inventories and depth profiling are determined. This study reveals the shielding and radioactivity issue of carbon ion therapy facilities and is expected to aid in the design or construction of similar facilities.


Subject(s)
Heavy Ion Radiotherapy , Neutrons , Ions , Radioisotopes , Carbon , Monte Carlo Method , Radiation Dosage
3.
Appl Radiat Isot ; 188: 110350, 2022 Oct.
Article in English | MEDLINE | ID: mdl-35816888

ABSTRACT

Carbon ions have become the most widely used particles in heavy-ion tumor therapy due to favorable physical and biological characteristics. The beam delivery system (BDS) and tumor tissues are directly bombarded with accelerated carbon ions, resulting in activation products in the components and the patient's body. The results of an experimental study and a Monte-Carlo simulation for the radioactivity induced in a treatment room under a uniform scanning mode were presented in this study. They indicated that the multi-leaf collimator (MLC) and the patient's body were the main sources of induced radioactivity. The half-lives of the main produced radionuclides ranged from a few minutes to tens of minutes for single irradiation and from dozens of days to hundreds of days for long-term irradiation. The personal dose of medical staff working in the treatment room and the additional dose of the patient from the induced radioactivity were estimated. Finally, some suggestions were made to reduce the unwanted radiation exposure of the medical staff, patients, and carers.


Subject(s)
Heavy Ion Radiotherapy , Neoplasms , Carbon/therapeutic use , Humans , Ions , Monte Carlo Method , Neoplasms/drug therapy , Radiotherapy Dosage , Radiotherapy Planning, Computer-Assisted/methods
4.
Radiat Prot Dosimetry ; 183(3): 312-318, 2019 May 01.
Article in English | MEDLINE | ID: mdl-30053202

ABSTRACT

The first Radioactive Ion Beam Line in Lanzhou was a projectile fragment separator located in the HIRFL. The process of production and separation of radioactive ion beams can induce a strong and complex radiation field. The neutron dose equivalent rates were measured in four positions with a 70 MeV/u 40Ar18+ beam. The results were compared with that simulated by the FLUKA code. New shielding walls were installed to reduce the neutron background for spectroscopy measurement in the experimental terminal. In addition, the induced radioactivity of accelerator components and corresponding residual dose rates were analyzed for the radiation safety of accelerator workers. The airborne radioactivity as well as occupational exposure due to immersion in and inhalation of activated air were also estimated. This work aims to provide a valuable experience for the radiation study in the future fragment separator HFRS at HIAF.


Subject(s)
Neutrons , Occupational Exposure/analysis , Particle Accelerators , Radiation Protection/methods , Air Pollutants, Occupational/analysis , China , Heavy Ions , Humans , Radiation Dosage
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