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1.
J Cancer Res Ther ; 15(1): 132-137, 2019.
Article in English | MEDLINE | ID: mdl-30880768

ABSTRACT

AIMS: Retrorectal tumors are rare, mostly benign tumors and named due to their localization. Diagnoses of these tumors are usually delayed because of nonspecific complaints and symptoms. Magnetic resonance imaging has beneficial uses both for diagnosis and treatment. In this study, we reviewed a case series of retrorectal tumors. SUBJECTS AND METHODS: The patients who were diagnosed with retrorectal tumors between 2008 and 2015 were analyzed. This investigation was conducted at a Tertiary Education and Research Hospital. Sixteen patients were included in this study. Patients' demographic data, imaging workups, surgical operation reports, pathologic examination results, postoperative complications, and follow-up results were examined. Descriptive statistics, median, and standard deviation for continuous variables were used. The primary outcomes measured were diagnostic conflict, knowledge, and preference for surgery. STATISTICAL ANALYSIS USED: Definitive statistical methods (mean, standard deviation, median, frequency, and percentage) were used to evaluate the study data. RESULTS: One patient refused operation and one was in preoperative preparation period. Fourteen of sixteen patients were operated. Two (14.3%) of operated patients have malignant histopathological result (one gastrointestinal stromal tumor, one ganglioneuroblastoma). Rest of the operated patients' histopathological reports was as follows: Four schwannomas, three epidermoid cysts, two tailgut cyst, one dermoid cyst, one teratoma, and one angiomyolipoma. Eight patients were operated by posterior incision, five patients with transabdominal approach, and one patient with combined approach. CONCLUSIONS: Retrorectal tumors are rare cases, and treatment of retrorectal tumors is surgery and should be operated in referenced hospitals to avoid diagnostic and therapeutic problems.


Subject(s)
Neoplasms, Germ Cell and Embryonal/surgery , Postoperative Complications/prevention & control , Rare Diseases/surgery , Sacrococcygeal Region/pathology , Adolescent , Adult , Aged , Diagnosis, Differential , Female , Follow-Up Studies , Hospitals, Teaching , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Neoplasms, Germ Cell and Embryonal/diagnostic imaging , Neoplasms, Germ Cell and Embryonal/pathology , Postoperative Complications/etiology , Prospective Studies , Rare Diseases/diagnostic imaging , Rare Diseases/pathology , Sacrococcygeal Region/diagnostic imaging , Sacrococcygeal Region/surgery , Tertiary Care Centers , Young Adult
2.
J Cancer Res Ther ; 14(6): 1355-1360, 2018.
Article in English | MEDLINE | ID: mdl-30488856

ABSTRACT

AIMS: Appendiceal mucocele (AM) is a rare pathology, and its reported incidence is 0.3% in all appendectomy specimens. Here, we report a case series of AM and make a brief review of literature. SUBJECTS AND METHODS: We conducted a retrospective review of a prospectively collected data of patients who diagnosed as AM by histopathological evaluation between January 2009 and June 2015 were demographic data including age and gender, intraoperative findings, and histopathological reports were recorded. All cases were followed-up by routine examination and telephone interview. STATISTICAL ANALYSIS USED: Definitive statistical methods (mean, standard deviation, median, frequency, and percentage) were used to evaluate the study data. RESULTS: Twelve patients were examined in the study with diagnose of AM. The mean age was 51.8 ± 18.6 years (26-83). Female-to-male ratio was 1.4 (7/5). Indications for surgery were acute abdomen in 8 (72.7%) patients with presumptive diagnosis of acute appendicitis and were AM in four patients diagnosed by imaging. Histopathological evaluation revealed mucinous cystadenoma in eight patients, simple retention cysts in three, and borderline mucinous tumor (pseudomyxoma peritonei) in one. The neuroendocrine tumor was obtained on the remaining portion of the appendix in one of the simple retention cysts patients. None of the patients died because of the AM with an average follow-up of 43 months (range: 7-74). CONCLUSIONS: Surgical resection is the first choice therapy for AM. Precise treatment modality can remain unclear in some patients because of insufficient preoperative diagnosis. It is nonmalign AM mostly however having mucocele matters because of the significant association with synchronous tumors.


Subject(s)
Appendicitis/diagnosis , Appendicitis/pathology , Appendix/pathology , Mucocele/diagnosis , Mucocele/pathology , Adult , Aged , Aged, 80 and over , Appendectomy/methods , Appendiceal Neoplasms/diagnosis , Appendiceal Neoplasms/pathology , Appendicitis/surgery , Appendix/surgery , Cystadenoma, Mucinous/diagnosis , Cystadenoma, Mucinous/pathology , Cystadenoma, Mucinous/surgery , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Mucocele/surgery , Prospective Studies , Retrospective Studies
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