ABSTRACT
Endoscopic investigation is a predominant stan-dard while assessing the gastrointestinal tract. Even though it has been rigorously used in diagnostics for many decades, a high miss rate has been recorded. Advanced endoscopic imaging still has not found solutions to problems like early cancer detection, polyp generality, disease classification, etc. One of the less explored techniques to study early cancer detection is spectral imaging which deals with the absorption and reflection spectra of various wavelengths of light by different layers of tissue. To study tissues under various illumination, a multi-spectral light source unit that can be used along with an endoscopy system was developed with 10 different LEDs of very narrow bandwidths. Using this light source, a feasibility study was per-formed on an animal in which the upper GI tract of a porcine model was imaged and sample images were taken for processing from five different sections. Some wavelengths showed better contrast enhancements for visualization of vascular structures. Wavelength 420 nm (violet light) showed better contrast and the gradient of the line profile histogram showed the highest intensity change between the blood vessels and the surrounding mucosa. These enhancements showed that spectral imaging can potentially help in studying tissues for early cancer detection and improved visualization of the G I tract using endoscopy.
