Results of the Modified Brosch Approach and Rehabilitation of Mural Unicystic Ameloblastoma of the Mandible in a Young Patient.

Although radical surgery results in craniofacial deformity, functional damage, and aesthetic harm, all of which have an immediate negative impact on a patient's quality of life, it also has the lowest recurrence rate for biologically aggressive subtypes of mural unicystic ameloblastomas. The oral approach removes the lingual cortex and exposes the entire buccal cortical plate in the area of the ascending and horizontal ramus to the full extent of the lesion. There is no obvious distortion of the soft tissues of the face following the modified Brosch procedure, which is also associated with rapid bone regeneration. This approach resulted in less invasive surgery and low surgical morbidity and recurrence in a young adult with a large mural unicystic ameloblastoma.

Recurrent Palatal Pleomorphic Adenoma: A Case Report With a Long-Term Follow-Up.

Pleomorphic adenoma is the most common kind of major tumor of the major and minor salivary organs. Although pleomorphic adenoma is a benign tumor, it has a high chance of recurrence and malignancy. In the literature, lower rates of repetitive pleomorphic adenoma of the sense of taste have been detailed while the palate is a common location for an intraoral pleomorphic adenoma. Recurring tumors have been associated with a high risk of malignancy, and surgical excision is the basic treatment option for recurrent adenomas. Revision surgery is quite challenging and has never been standardized. We report a rare case of recurrent pleomorphic adenoma of the palate that occurred 7.5 years after primary ablation.

Expression of Sex Hormones in Oral Squamous Cell Carcinoma: A Systematic Review on Immunohistochemical Studies.

Oral squamous cell carcinoma (OSCC) is the most widespread oral malignancy. In the western world, smoking and alcohol remain the most common risk factors, whereas smokeless tobacco and areca nut consumption are the prevalent etiological factors in South Asia. Numerous markers were studied till date to identify the disease. However, the role of sex hormones in OSCC is poorly defined. Hormonal receptors play a role in breast cancer, prostate cancer, and human papillomavirus (HPV) driven oropharyngeal cancers. It is proven that the expression of estrogen receptor-α improved the overall survival of the patient with HPV-positive oropharyngeal cancer. Thus, this review article aims to determine the expression of sex hormones by immunohistochemistry in OSCC. This systematic review was performed with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement Criteria 2020. Relevant articles were collected from the electronic database in PubMed and Cochrane till 2021. Immunohistochemical studies on sex hormones and their role in OSCC published in English literature were included. We excluded case reports, case series, and abstract-only articles. The sample size of the selected studies varied, and these studies measured the parameters such as sex hormones and OSCC. Furthermore, all the studies used different sex hormones and their association with oral cancer through the immunohistochemical process. Thus, this review summarizes that sex hormones influence the biopathology of oral cancer and have a prognostic significance in the tumor subgroups.

An Intraosseous Giant Cell Granuloma: An Uncommon Presentation.

The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant. The central form of giant cell granuloma involves the craniofacial bone, followed by long bones of hands and feet. These lesions are usually asymptomatic lesions and are discovered incidentally during routine radiographic examination. Radiograph features reveal multilocular jaw lesions, generally anterior to the first molar regions. Histologically, the lesion shows proliferating spindle-shaped stromal cells in a fibrovascular connective tissue stroma, which characteristically contains multiple multinucleated giant cells. Hemorrhage and hemosiderin pigmentations are often seen in tumor. Central giant cell granuloma is often confused with giant cell tumor of bone histologically. Here, we report a young male who was found to have large central giant cell granuloma in the anterior part of the mandible. The surgical treatment approach of central giant cell granuloma is discussed in this article.

A Rare Incidence of Metachronous Neurovascular Lesions in a Child.

Neurofibroma is an uncommon benign tumor arising from nerve sheath fibroblasts. The diagnosis of solitary lesions becomes difficult in patients who do not have any family history of neurofibroma. An intra-oral solitary neurofibroma comprises 6.5% of reported cases of neurofibroma. Few cases of intraosseous solitary neurofibroma have been published as per literature. Treatment-surgical resection of tumor has an excellent prognosis with extreme rare malignant transformation which is more commonly seen in neurofibromatosis. A periodic follow-up is necessary in solitary tumors to rule out syndromic cases. Leiomyoma is a benign tumor of smooth muscle origin, which is usually diagnosed in the gastrointestinal tract, uterus, and skin. The most effective treatment for solid, vascular, and epithelioid angioleiomyomas is surgical resection along with tumor capsule. Here we report an uncommon occurrence of multiple benign tumors in a pediatric patient.

Revisiting Cementoblastoma with a Rare Case Presentation.

Cementoblastoma is a rare benign odontogenic neoplasm which is characterized by the proliferation of cellular cementum. Diagnosis of cementoblastoma is challenging because of its protracted clinical, radiographic features, and bland histological appearance; most often cementoblastoma is often confused with other cementum and bone originated lesions. The aim of this article is to overview/revisit, approach the diagnosis of cementoblastoma, and also present a unique radiographic appearance of a cementoblastoma lesion associated with an impacted tooth.