Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 7 de 7
Filter
Add more filters










Database
Publication year range
1.
Jpn J Thorac Cardiovasc Surg ; 49(2): 103-7, 2001 Feb.
Article in English | MEDLINE | ID: mdl-11257764

ABSTRACT

OBJECTIVE: For patients diagnosed with combined thoracic aortic aneurysms and cardiac lesions, we conduct a 1-stage operation for ascending and aortic arch grafting. We studied surgical outcome comparatively with patients undergoing aortic grafting alone. For descending and thoracoabdominal aortic grafting, we choose a 2-stage operation. SUBJECTS AND METHODS: Subjects were 80 patients undergoing ascending and aortic arch aneurysm repair between June 1994 and March 1999. Group 1 consisted of 30 undergoing simultaneous cardiac repair. Concomitant cardiac procedures involved 21 valvular, 5 coronary arterial, and 4 valvular and coronary arterial surgeries. Group 2 consisted of 50 undergoing aortic grafting alone. We used crystalloid cardioplegia and additional antegrade continuous cold-blood coronary perfusion in Group 1, and crystalloid cardioplegia alone in Group 2. RESULTS: Hospital mortality was 10% in Group 1 and 2% in Group 2. Surgery length, cardiopulmonary bypass time, and aortic cross-clamping time in Group 1 were significantly longer than Group 2. Myocardial ischemic time did not differ significantly. Postoperative ICU stay, mechanical ventilation time and catecholamine support time did not differ significantly. Actuarial survival was 66.9 +/- 13.1% at 52 months in Group 1 and 87.2 +/- 4.8% at 57 months in Group 2 (p = 0.2918). CONCLUSION: Simultaneous cardiac repair and ascending and aortic arch aneurysm repair were conducted using continuous cold-blood coronary perfusion. Hospital mortality and mid-term survival did not differ significantly between groups.


Subject(s)
Aortic Aneurysm, Thoracic/surgery , Cardiac Surgical Procedures/methods , Coronary Circulation , Coronary Disease/surgery , Perfusion/methods , Aged , Aorta/surgery , Aorta, Thoracic/surgery , Blood , Female , Heart Valve Diseases/surgery , Hospital Mortality , Humans , Male , Middle Aged
2.
Jpn J Thorac Cardiovasc Surg ; 48(8): 531-3, 2000 Aug.
Article in English | MEDLINE | ID: mdl-11002587

ABSTRACT

Aorto-right atrium fistula associated with aortic dissection is a very rare complication. Here report a case of successful surgical repair of ascending aortic dissection complicated with aorto-right atrium fistula. A 65-year-old man was presented with sudden chest pain and dyspnea. Fifteen years ago, he had aortic valve replacement. An aortic dissection with fistula to the right atrium was diagnosed by echocardiography and cardiac catheterization. At operation, dense adhesion of the aortic root due to the previous cardiac operation was confirmed, and this was suggested as the cause for this rare complication.


Subject(s)
Aortic Aneurysm/complications , Aortic Diseases/complications , Aortic Dissection/complications , Fistula/complications , Heart Diseases/complications , Vascular Fistula/complications , Aged , Aortic Dissection/surgery , Aortic Aneurysm/surgery , Aortic Diseases/surgery , Fistula/surgery , Heart Atria , Heart Diseases/surgery , Humans , Male , Vascular Fistula/surgery
3.
Nihon Kyobu Geka Gakkai Zasshi ; 43(8): 1097-102, 1995 Aug.
Article in Japanese | MEDLINE | ID: mdl-7594841

ABSTRACT

Long-term follow up results of valve replacement with Carpentier-Edwards pericardial bioprosthesis were analysed. From April 1985 to March 1994, a total of 99 bioprostheses were implanted in 92 patients. Aortic valve replacement was performed in 27, mitral valve replacement in 43, combined aortic-mitral valve replacement in 7 and tricuspid valve replacement in 15 patients. The actuarial survival rates at 9 years were 84% (aortic), 59% (mitral), 69% (aortic-mitral) and 76% (tricuspid) respectively. One patient sustained a thromboembolic event after mitral valve replacement, however, none of that complication occurred after aortic or tricuspid valve replacement. Two patients with mitral valve replacement required reoperation because of structural deterioration after 8 years. Five cases of bioprosthetic infection encountered, and three died. Actuarial freedom from overall valve-related complications at 9 years was 97% for aortic, 72% for mitral and 100% for tricuspid valve replacement respectively. There was no structural deterioration of the aortic and tricuspid valve. Actuarial freedom from structural deterioration of the mitral valve was 84% at 9 years. We conclude that the Carpentier-Edwards pericardial bioprosthesis has low incidence of valve related complication within the 9 years time frame of this study.


Subject(s)
Bioprosthesis , Heart Valve Diseases/surgery , Heart Valve Prosthesis/mortality , Adult , Age Factors , Aged , Female , Follow-Up Studies , Humans , Male , Middle Aged , Prosthesis Failure , Survival Rate , Time Factors
4.
Gan To Kagaku Ryoho ; 18(6): 1031-8, 1991 May.
Article in Japanese | MEDLINE | ID: mdl-2029188

ABSTRACT

We thought that nutritional parameters in laboratory data might be able to express quality of life (QOL). Therefore, in 70 patients with malignant chest diseases (NSCLC, 42 patients; SCLC, 15; lung metastasis, 7; others, 6), the correlation between nutritional parameters of total protein (Tp), serum albumin (Alb), and serum (cholinesterase (ChE] and Karnofsky Performance Status scale (KPS) was investigated. Then, in 24 patients with them (NSCLC, 12; SCLC, 6; lung metastasis, 4; others 2), Alb and ChE were compared to the EORTC Core Quality of Life Questionnaire and Lung Cancer-Specific Questionnaire Module (QS). Results were as follows: 1) KPS and nutritional parameters correlated (Tp. r = 0.55, p less than 0.001; Alb, r = 0.60, p less than 0.001, ChE, r = 0.60; p less than 0.001). 2) The cores for Functional Status (FS) and Disease and Treatment-related symptoms (Sym) in QS and parameters of Alb and ChE correlate (FS v.s. Alb, p less than 0.01; Sym v.s. Alb, p less than 0.01; FS v.s. ChE, p less than 0.05; and Sym v.s. ChE, p less than 0.05). Moreover, the scores of Psychological Distress in QS and Alb showed a correlation (p less than 0.05). It is considered that nutrition and part of QOL (KPS and FS + Sym in QS, that is to say, "objective" functional activity and "subjective" functional activity and symptoms) correlate, and that nutritional parameters are useful to evaluate QOL.


Subject(s)
Neoplasms/rehabilitation , Nutritional Physiological Phenomena , Quality of Life , Humans , Lung Neoplasms/psychology , Lung Neoplasms/rehabilitation , Neoplasms/psychology , Nutrition Assessment , Serum Albumin/analysis , Surveys and Questionnaires
5.
Jpn J Antibiot ; 42(8): 1745-50, 1989 Aug.
Article in Japanese | MEDLINE | ID: mdl-2810738

ABSTRACT

Cefteram pivoxil (CFTM-PI), a newly developed oral cephem antibiotic was administered to treat 16 children with various infections. The results were summarized as follows. 1. The clinical responses were "excellent" in 7, "good" in 5, "fair" in 3 and "poor" in 1, with 75.0% efficacy rate. 2. No side effects and no abnormal laboratory findings were observed.


Subject(s)
Bacterial Infections/drug therapy , Cefmenoxime/analogs & derivatives , Cefmenoxime/administration & dosage , Cefmenoxime/therapeutic use , Child , Child, Preschool , Drug Evaluation , Female , Humans , Infant , Male
6.
Nihon Jinzo Gakkai Shi ; 31(1): 91-7, 1989 Jan.
Article in Japanese | MEDLINE | ID: mdl-2747003

ABSTRACT

Incubation of normal human serum with hemodialysis membranes in vitro resulted in conversion of C3 which was detected by crossed immunoelectrophoresis. In addition, formation of C3d was also observed, as was detected by double-decker rocket immunoelectrophoresis. Furthermore, breakdown products of complement (iC3b, C4d & Bb) in plasma samples were measured by ELISA. The microassay plates were coated with monoclonal antibodies which bind specifically to human iC3b, C4d and Bb, respectively, while the plasma samples were drawn from five polycystic kidney patients during initial hemodialysis. As a result, the iC3b and Bb levels in plasma were seen to increase during hemodialysis but the C4d levels revealed no significant changes. It was also observed that the Bb levels in patients undergoing hemodialysis were significantly higher than those in various renal and collagen diseases. Terminal complement complex (TCC) was not present in detectable amounts in normal human serum when measured by ELISA. However, incubation of normal human serum with hemodialysis membranes in vitro resulted in detection of TCC. TCC was present in the same plasma samples drawned from the five polycystic kidney patients during initial hemodialysis. It is suggestive that activation of complement by hemodialysis membrane is predominantly mediated through the alternative pathway and products such as TCC and anaphylatoxin are formed by this activation.


Subject(s)
Complement Activation , Complement System Proteins/metabolism , Renal Dialysis/adverse effects , Complement Membrane Attack Complex , Complement Pathway, Alternative , Humans , Immune Tolerance , Membranes, Artificial
SELECTION OF CITATIONS
SEARCH DETAIL
...