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1.
Neuroreport ; 22(11): 515-9, 2011 Aug 03.
Article in English | MEDLINE | ID: mdl-21673607

ABSTRACT

We investigated the neural basis of iconic memory using functional magnetic resonance imaging. The parietofrontal network of selective attention is reportedly relevant to readout from iconic memory. We adopted a temporal integration task that requires iconic memory but not selective attention. The results showed that the task activated the parietofrontal network, confirming that the network is involved in readout from iconic memory. We further tested a condition in which temporal integration was performed by visual short-term memory but not by iconic memory. However, no brain region revealed higher activation for temporal integration by iconic memory than for temporal integration by visual short-term memory. This result suggested that there is no localized brain region specialized for iconic memory per se.


Subject(s)
Frontal Lobe/physiology , Memory/physiology , Nerve Net/physiology , Parietal Lobe/physiology , Attention/physiology , Data Interpretation, Statistical , Female , Functional Laterality/physiology , Humans , Image Processing, Computer-Assisted , Magnetic Resonance Imaging , Male , Memory, Short-Term/physiology , Photic Stimulation , Psychomotor Performance/physiology , Reaction Time/physiology , Young Adult
2.
J Nat Prod ; 69(8): 1252-4, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16933891

ABSTRACT

A new bisindole sulfate (1) and arcyroxocin B (2) were isolated from wild fruiting bodies of Arcyria denudate, along with three known bisindoles (4-6). Dihydroarcyriacyanin A (3) was obtained from wild fruiting bodies of Arcyria obvelata, along with a known bisindole (7). The structures of these compounds were elucidated on the basis of spectroscopic data, and this is the first report of full characterizations of arcyroxocin B (2) and dihydroarcyriacyanin A (3). Compounds 2, 3, and 6 showed cytotoxicity against Jurkat cells.


Subject(s)
Indole Alkaloids/isolation & purification , Myxomycetes/chemistry , Drug Screening Assays, Antitumor , Fruiting Bodies, Fungal/chemistry , Humans , Indole Alkaloids/chemistry , Indole Alkaloids/pharmacology , Inhibitory Concentration 50 , Jurkat Cells , Molecular Structure , Nuclear Magnetic Resonance, Biomolecular
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