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1.
Gan To Kagaku Ryoho ; 50(13): 1390-1392, 2023 Dec.
Article in Japanese | MEDLINE | ID: mdl-38303284

ABSTRACT

A 63-year-old female patient was diagnosed with cecal cancer(cT3, N2a, M0)and underwent surgery for the first time. Only laparoscopic ileocecal resection(D3 dissection)was performed because intraperitoneal observation revealed peritoneal metastasis around the tumor and uterus. We decided to perform a radical resection because the peritoneal metastasis was localized by FDG-PET/CT. Five courses of neoadjuvant chemotherapy(mFOLFOX6)were performed to shrink the tumor. Unrecognized peritoneal metastases were found in other areas during the second surgery. Although the extent of the peritoneal metastasis was P3, all lesions had been resected. No perioperative complications occurred, and adjuvant chemotherapy was administered to the patient. Recurrence was not observed until 6 months postoperatively.


Subject(s)
Cecal Neoplasms , Laparoscopy , Peritoneal Neoplasms , Female , Humans , Middle Aged , Peritoneal Neoplasms/drug therapy , Peritoneal Neoplasms/surgery , Peritoneal Neoplasms/secondary , Positron Emission Tomography Computed Tomography , Neoadjuvant Therapy , Cecal Neoplasms/drug therapy , Cecal Neoplasms/surgery , Cecal Neoplasms/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use
2.
Gan To Kagaku Ryoho ; 43(9): 1101-3, 2016 Sep.
Article in Japanese | MEDLINE | ID: mdl-27628552

ABSTRACT

A 52-year-old woman presented with redness and swelling with a peau d'orange appearance in the whole right breast. Ultrasound revealed elevated subcutaneus fat density and a diffuse hypoechoic area. She was diagnosed with inflammatory breast cancer(T4dN2M0, Stage III B of the HER2 subtype). After 4 courses of EC treatment as primary systemic therapy, the hypoechoic area was still present. Subsequent chemotherapy with pertuzumab, trastuzumab, and docetaxel was effective, as hypoechoic area was not observed on ultrasound. She underwent mastectomy and axillary dissection, and pathological examination revealed pCR. At present, 2 years after surgery, the patient is alive with no reccurence.


Subject(s)
Antibodies, Monoclonal, Humanized/therapeutic use , Inflammatory Breast Neoplasms/drug therapy , Neoadjuvant Therapy , Biopsy , Female , Humans , Inflammatory Breast Neoplasms/chemistry , Inflammatory Breast Neoplasms/pathology , Inflammatory Breast Neoplasms/surgery , Mastectomy , Middle Aged , Neoplasm Staging , Receptor, ErbB-2/analysis , Receptor, ErbB-2/metabolism , Treatment Outcome
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