[Characteristics of the action of extracts of pink-stained grain of fusarial and nonfusarial origin on the structure of the organs in growing rat pups]. / Osobennosti deistviia ékstraktov iz rozovookrashennogo zerna fuzarioznoi i nefuzarioznoi prirody na strukturu organov rastushchikh krysiat.

The characteristics of the toxic effect of rose-stained grain of fusarial and non-fusarial nature, as well as the grain experimentally challenged with the toxic strain Fusarium sporotrichiella 53315, were studied basing on the analysis of morphological changes in the internal organs of young rat given orally extracts from the samples studied. The tissue aging processes under the effect of the extract doses producing no irreversible pathologic changes were investigated. It was shown that the extracts of rose-stained natural grain, fusarial and without signs of fusaridiosis, produced similar pathological changes in the morphological structures of the organs in the young rats, the toxicity grew with the increase of the per cent of rose-stained grain. Dystrophic changes in the parenchymatous organs and impairment of the structure of the immunogenesis organs were recorded with a low content of rose-stained grain (3-3.5%), the changes in some organs at the structural and cellular level were also revealed, however, they were less manifest and evidenced a regional antigenic stimulation.

[Dynamics of serum immunoglobulin concentrations in the rabbit during experimental food anaphylaxis]. / Dinamika soderzhaniia immunoglobulinov v syvorotke krolikov v khode éksperimental'noi pishchevoi anafilaksii.

The content of serum IgG, IgM and IgG was studied in rabbits at varying times of oral sensitization of animals before and after administration of the resolving dose of food protein. The content of IgG was found to be reduced on the 19th-21st day of sensitization. Meanwhile the content of IgA increased on the 24th day of oral sensitization. Administration of the resolving dose of protein on the 19th day of sensitization was followed by the reduction of IgG content. A reverse correlation was revealed between the changes in the content of IgG and the degree of food anaphylaxis in rabbits.

[Cytological organization of the gastric glands, small intestine cryptae and cortical substance of the adrenals in rats]. / Tsitologicheskaia organizatsiia zhelez zheludka, kript tonkikh kishok i korkovogo veshchestva nadpochechnika krys.

The frequency of distribution of DNA-synthesizing cells in the intestinal crypt, in the gland of the fundus of the stomach and adrenocortical substance was studied in rats in terms of the age aspect. The common features of cytologic organization of the test organs are as follows: irregularity in the location of DNA synthesis and mitotic zones along the linear structure of an organ; density of the features investigated in the structure of an organ depending on the cell position and animal age; shortening with age of the zone of cell division in the hepatic balk, gastric glands and intestinal crypt.

[Aging of the intima of the human thoracic aorta]. / Starenie intimy grudnoi aorty cheloveka.

The aging of the intima of the human thoracic aorta was studied on autopsy material collected from individuals aged from 1 day to 99 years. It has been established that the density of the cell population and the thickness of the intima and the content of cholesterol and phospholipids in it are signs of intima aging. There is an exponential relation between these signs and the age of an individual. The level of cholesterol concentration in the intima depends on its thickness.

[Migration of hepatocytes in liver cords during physiologic regeneration]. / Peremeshchenie gepatotsitov v pechenochnoi balke pri fiziologicheskoi regeneratsii

Distribution of mitoses and dead hepatocytes in the hepatic balk was investigated. A relative rate of the hepatocyte movement along the hepatic balk was calculated on the basis of this distribution. The direction and the rate of the hepatocyte movement along the hepatic balk were determined by measurement of the shift of the labelled cell peak a month after six thymidine-H3 injections.

[Cytological organization of the hepatic ligament in rats]. / Tsitologicheskaia organizatsiia pechenochnoi balki u krys

A method of integration frequencies of distribution of classes of hepatocytes, DNA-synthesising cells and mitoses along the hepatic balk was applied to the study of the cytological organization of the balk in rats of different age. Distribution of subpopulations of hepatocytes in the hepatic balk displayed distinct features of space organization: most of mitoses and of the DNA-synthesizing hepatocytes were localized at the beginning of the balk, the first nuclear class prevailed at the beginning and the end of the balk, and the second class--in the middle of the balk. The results presented served as an additional confirmation of the presence of self-renewal processes in the liver of adult rats.