1.
Org Lett
; 11(21): 5054-7, 2009 Nov 05.
Article
in English
| MEDLINE
| ID: mdl-19863154
ABSTRACT
An efficient method for the selective "N1" alkylation of indazoles is described. Use of alpha-halo esters, lactones, ketones, amides, and bromoacetonitrile provides good to excellent yield of the desired N1 products.