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Urol Nefrol (Mosk) ; (4): 7-9, 1996.
Article in Russian | MEDLINE | ID: mdl-8928353

ABSTRACT

The author's investigations led them to the conclusion that clinical manifestation of chronic pyelonephritis is associated with destabilization of lipid bilayer of red cell membranes, renal tissue, activation of lipid peroxidation (LPO), rising lipid and LPO products excretion with the urine. 31 patients with chronic pyelonephritis received combined therapy comprising essential phospholipids. 25 control patients with the same disease were not given essentiale-forte. Finally, the latter had longer fever duration, more active inflammation. The former had also low urine excretion of oxalates and normal lipid composition of biological membranes.


Subject(s)
Phosphatidylcholines/therapeutic use , Pyelonephritis/drug therapy , Adolescent , Adult , Chronic Disease , Drug Evaluation , Erythrocyte Membrane/drug effects , Erythrocyte Membrane/metabolism , Female , Humans , Lipid Peroxidation/drug effects , Male , Membrane Lipids/metabolism , Middle Aged , Phosphatidylcholines/adverse effects , Pyelonephritis/diagnosis , Pyelonephritis/metabolism , Urinary Calculi/diagnosis , Urinary Calculi/drug therapy , Urinary Calculi/metabolism
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