Oral mucosa alterations in chronic hepatitis and cirrhosis due to HBV or HCV infection.

The aim of the study was to evaluate the character of lesions within oral mucosa in patients suffering from chronic hepatitis and cirrhosis of the liver due to either HBV or HCV infection. A total of 74 patients treated at the Clinic of Infectious Diseases in Wroclaw for chronic hepatitis B (20 patients, group I) and for chronic hepatitis C (23 patients group III) and cirrhosis of the liver due to HBV (15 patients , group II) and HCV (16 patients, group IV) infection. The control group comprised 29 healthy subjects. Lesions within the oral mucosa found on clinical examinations were confirmed with a histopathological evaluation. Patients suffering from chronic hepatitis B revealed leukoplakia (1/20), melanoplakia (1/20), petechiae (1/20), 17 patients from this group did not show any changes. Patients suffering from chronic hepatitis C revealed leukoplakia (6/23), Delbanco's disease (2/23), melanoplakia (1/23), lichen planus (1/23), petechiae (1/23), 12 patients from this group did not show any changes. Patients suffering from cirrhosis of the liver due of HBV infection revealed leukoplakia (3/15) petechiae (2/15), Delbanco's disease (1/15), angular cheilitis (1/15), aphthae (1/15), 7 patients from this group did not reveal any changes. Patients suffering from cirrhosis of the liver due of HCV infection revealed petechiae (2/16), melanoplakia (1/16), candidosis (1/16), labial herpes (1/16), 11 patients from this group did not reveal any changes. In control group we observed leukoplakia (3/29), Delbanco's disease (1/29), labial herpes (1/29), petechiae (1/29), and 23 subjects did not present pathological lesions within the oral mucosa. Results indicate the lack of connection between chronic HBV and HCV infection as well as the stage of the disease with the incidence and character of oral lesions in oral mucosa.

Correlation between temporomandibular dysfunction, disturbances of occlusion and gingival recession in a group of youth students.

UNLABELLED: The aim of this study was to investigate the relation between temporo-mandibular dysfunction (TMD), and disturbances of occlusion and gingival recession (GR) in a group of youth students. METHODS: The following measurements were performed: Anamnestic Index by Helkimo (AI), Diagnostic Index by Helkimo (DI), clinical evaluation of centric (CO) and excentric (EO) occlusion, clinical estimation of malocclusion and tooth malposition, anamnestic and clinical analysis of the occurrence of occlusal and non-occlusal parafunctions, anamnestic dysfunction of the vertebral column (ADVC), number of patients with GR > or = and/or < or = 2mm. RESULTS: Higher incidence of malposition teeth and ADVC were noted in a group of patients with CO disturbances. In the group of patients with disturbances of EO a significant higher number of patients with GR < or = 2 mm and a significant malposition of the teeth was observed. In the group of patients with clinical dysfunctions of TMD anamnestic dysfunction was more frequent. In the group of patients with GR a significant dependence on the age was proved. In this group there was also an increased occurrence of malposition of the teeth as well as malocclusions. The multifactor etiology of TMD and GR shows necessity of the more sharp diagnosis based on the movement system test.

[The influence of HCV infection and immunomodulating therapy (interferon-alpha and ribavirin) on the condition of minor salivary glands and oral mucosa]. / Wplyw zakazenia HCV i leczenia immunomodulacyjnego interferonem - alfa I ribaviryna na stan drobnych gruczolów slinowych i blony sluzowej jamy ustnej.

The aim of the study was to determine an influence of HCV infection and combination therapy with interferon - alpha and ribavirin on the condition of oral mucosa and minor salivary glands in patients with chronic hepatitis C in comparison to subjects without liver pathology on 12-month follow-up. Patients with chronic hepatitis C more commonly develop pathological changes on the oral mucosa than patients without liver pathology. Combination therapy affects the amount of pathological lesions in the oral cavity of patients suffering from chronic hepatitis C and B. The occurrence of oral lichen planus on the oral mucosa may be associated with chronic hepatitis C as well as with concomitant alpha-interferon and antiviral therapy.