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Aging Ment Health ; 12(6): 675-83, 2008 Nov.
Article in English | MEDLINE | ID: mdl-19023719

ABSTRACT

OBJECTIVES: This investigation examined the associations between self-reports, collateral-source reports and a clinician's diagnosis of depression in persons with cognitive impairment. METHOD: Responses on the Geriatric Depression Scale - 15 (GDS-15) from 162 participants with a diagnosis of Mild Cognitive Impairment (n = 78) or Alzheimer's Dementia and a Mini-Mental State score >or=15 (n = 84) were compared with both their collateral sources' report on either the Neuropsychiatric Inventory Questionnaire (n = 93) and/or the collateral-source GDS-15 (n = 67), or a clinician's diagnosis of Major Depression (MD). RESULTS: Significant differences were seen between self- versus collateral-source reports of depression in these participants. Participants' reports of loss of interest (anhedonia) significantly increased the odds of disagreement with their collateral sources (OR = 3.78, 95% CI: 1.3-11.2) while reports of negative cognitions significantly decreased the odds of such a disagreement (OR = 0.31, 95% CI: 0.1-0.9). The symptom of anhedonia also showed the strongest association with the clinician's diagnosis of MD. CONCLUSION: A motivational symptom like loss of interest was seen to play an important role in depression experienced by those with cognitive impairment.


Subject(s)
Cognition Disorders/psychology , Dementia/psychology , Depressive Disorder/diagnosis , Psychiatric Status Rating Scales/statistics & numerical data , Activities of Daily Living , Aged , Aged, 80 and over , Arkansas , Cognition Disorders/complications , Dementia/complications , Depressive Disorder/complications , Depressive Disorder/psychology , Female , Humans , Logistic Models , Male , Multivariate Analysis , Neuropsychological Tests , Psychometrics , Self Concept , Severity of Illness Index , Surveys and Questionnaires
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