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1.
PNAS Nexus ; 3(7): pgae219, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38948018

ABSTRACT

Increased demands for sustainable water and energy resources in densely populated basins have led to the construction of dams, which impound waters in artificial reservoirs. In many cases, scarce field data led to the development of models that underestimated the seepage losses from reservoirs and ignored the role of extensive fault networks as preferred pathways for groundwater flow. We adopt an integrated approach (remote sensing, hydrologic modeling, and field observations) to assess the magnitude and nature of seepage from such systems using the Grand Ethiopian Renaissance Dam (GERD), Africa's largest hydropower project, as a test site. The dam was constructed on the Blue Nile within steep, highly fractured, and weathered terrain in the western Ethiopian Highlands. The GERD Gravity Recovery and Climate Experiment Terrestrial Water Storage (GRACETWS), seasonal peak difference product, reveals significant mass accumulation (43 ± 5 BCM) in the reservoir and seepage in its surroundings with progressive south-southwest mass migration along mapped structures between 2019 and 2022. Seepage, but not a decrease in inflow or increase in outflow, could explain, at least in part, the observed drop in the reservoir's water level and volume following each of the three fillings. Using mass balance calculations and GRACETWS observations, we estimate significant seepage (19.8 ± 6 BCM) comparable to the reservoir's impounded waters (19.9 ± 1.2 BCM). Investigating and addressing the seepage from the GERD will ensure sustainable development and promote regional cooperation; overlooking the seepage would compromise hydrological modeling efforts on the Nile Basin and misinform ongoing negotiations on the Nile water management.

2.
Int J Biol Macromol ; 272(Pt 1): 132847, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38834115

ABSTRACT

This study explored the impact of sodium hydroxide and benzoylation treatment on the production of cellulose nanocrystals from Semantan bamboo (Gigantochloa scortechinii). Bamboo cellulose nanocrystals (BCNs) were obtained via acid hydrolysis, with the effectiveness of an isolation method and chemical treatments demonstrated in removing non-cellulosic constituents. X-ray diffraction analysis revealed a crystalline cellulose II structure for benzoylated BCN (B) and a crystalline cellulose I structure for NaOH-treated BCN (S), with BCN (S) exhibiting a higher crystallinity index (80.55 %) compared to BCN (B) (67.87 %). The yield of BCN (B) (23.68 ± 1.10 %) was higher than BCN (S) (20.65 ± 2.21 %). Transmission electron microscopy images showed a mean diameter of 7.95 ± 2.79 nm for BCN (S) and 9.22 ± 3.38 nm for BCN (B). Thermogravimetric analysis indicated lower thermal stability for BCN (B) compared to BCN (S), with charcoal residues at 600 °C of 31.06 % and 22 %, respectively. Zeta potential values were -41.60 ± 1.97 mV for BCN (S) and -21.80 ± 2.54 mV for BCN (B). Gigantochloa scortechinii holds significant potential for sustainable and eco-friendly applications in the construction, furniture, and renewable energy industries. These findings highlight the versatility and potential of BCNs derived from Gigantochloa scortechinii for various applications.


Subject(s)
Cellulose , Nanoparticles , Cellulose/chemistry , Nanoparticles/chemistry , Poaceae/chemistry , Hydrolysis , X-Ray Diffraction
3.
Ital J Food Saf ; 13(2): 11854, 2024 May 15.
Article in English | MEDLINE | ID: mdl-38846045

ABSTRACT

Food security is critical for promoting health and well-being and achieving sustainable development, especially in developing countries. Despite the recent efforts to improve it, food security is still a concern due to the rapid increase in populations, conflicts, and natural disasters worldwide. Universities, particularly agricultural universities, play an essential role in addressing food security issues by researching, developing new technologies, and providing education and training to farmers and other stakeholders. The main objective of this review is to discuss the role of universities and integrated farming in ensuring food security, specifically in Malaysia. It includes a brief overview of the different types of integrated farming methods that can be used to improve food security and finally discusses the Student Farmer Entrepreneur program, which can be crucial for promoting food security by increasing agricultural productivity, promoting local food production, encouraging sustainable agriculture practices, and supporting rural development. This review also considers the significant impact of the Malaysian government and universities on food security. With integrated farming and the Student Farmer Entrepreneur program, food security can be further improved.

4.
Radiol Case Rep ; 19(8): 3283-3286, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38812591

ABSTRACT

A jejunal intussusception as a presentation of retroperitoneal liposarcoma (RLPS) is a rare occurrence. The majority of RLPS are presented as an abdominal mass, however, having a jejunal obstruction is an interesting case. The aim is to describe the management of jejunal intussusception secondary to atypical lipomatous tumours with concurrent RLPS. A 61-year-old lady presented with a sudden onset of intestinal obstruction with 1 month of constitutional symptoms and an enlarging right lumbar mass. Computed tomography showed a small bowel intussusception with diffuse peritoneal and retroperitoneal lipomatosis. Emergency exploratory laparotomy, segmental bowel resection, and partial excision of intraperitoneal mesenteric lipoma were performed. A stage En-bloc resection of the RLPS and right nephrectomy was done later. However, she refused for subsequent surgery. A complete resection is the gold standard in managing RLPS. In this report, the management is rendered not to the standard as the patient first presented with intestinal obstruction requiring emergency reduction with a piecemeal resection. A stage surgery was required to determine a promising prognosis, but the patient refused such surgery. A small bowel intussusception in adults is rare but is mostly caused by a tumor or neoplasm. Early recognition of the complexity of the case should be preempted and referred to the tertiary team for further definitive surgery. Patient exhaustion from the subsequent surgery might hamper the only management available for the case.

5.
Mol Genet Genomics ; 299(1): 56, 2024 May 24.
Article in English | MEDLINE | ID: mdl-38787424

ABSTRACT

Breast cancer (BC) is a heterogenous disease with multiple pathways implicated in its development, progression, and drug resistance. Autophagy, a cellular process responsible for self-digestion of damaged organelles, had been recognized as eminent player in cancer progression and chemotherapeutic resistance. The haploinsufficiency of Beclin 1 (BECN1), autophagy protein, is believed to contribute to cancer pathogenesis and progression. In our study, we investigated the expression of BECN1 in a BC female Egyptian patient cohort, as well as its prognostic role through evaluating its association with disease free survival (DFS) after 2 years follow up and association of tumor clinicopathological features. Twenty frozen female BC tissue samples and 17 adjacent normal tissue were included and examined for the expression levels of BECN1. Although the tumor tissues showed lower expression 0.73 (0-8.95) than their corresponding normal tissues 1.02 (0.04-19.59), it was not statistically significant, p: 0.463. BECN1 expression was not associated with stage, nodal metastasis or tumor size, p:0.435, 0.541, 0.296, respectively. However, statistically significant negative correlation was found between grade and BECN1 mRNA expression in the studied cases, p:0.028. BECN1 expression had no statistically significant association with DFS, P = 0.944. However, we observed that triple negative (TNBC) cases had significantly lower DFS rate than luminal BC patients, p: 0.022, with mean DFS 19.0 months, while luminal BC patients had mean DFS of 23.41 months. Our study highlights the potential role of BECN1 in BC pathogenesis, showing that BECN1 expression correlates with poorer differentiation of BC, indicating its probable link with disease aggressiveness. DFS two years follow up showed that TNBC subtype remains associated with less favorable prognosis.


Subject(s)
Beclin-1 , Breast Neoplasms , Neoplasm Grading , RNA, Messenger , Humans , Female , Beclin-1/genetics , Beclin-1/metabolism , Breast Neoplasms/genetics , Breast Neoplasms/pathology , Middle Aged , Adult , RNA, Messenger/genetics , RNA, Messenger/metabolism , Prognosis , Gene Expression Regulation, Neoplastic , Disease-Free Survival , Biomarkers, Tumor/genetics , Aged , Egypt
6.
BMC Anesthesiol ; 24(1): 180, 2024 May 21.
Article in English | MEDLINE | ID: mdl-38773360

ABSTRACT

BACKGROUND: Although the efficacy and safety of epidural block (EB) are fairly high, complications such as inadvertent dural puncture may limit its use. Ultrasound-guided quadratus lumborum block (QLB) is a relatively new regional technique that provides perioperative somatic and visceral analgesia for pediatric patients. This trial compared the quality of pain relief in pediatric patients undergoing abdominal surgery who received either QLB or EB. METHODS: Patients were randomly allocated into two equal groups: Group E(n = 29): received EB; Group QL(n = 29): received QLB. Both groups were injected with 0.25% bupivacaine (0.5 ml/kg). Assessment of total analgesia consumption was the primary outcome measure, whereas the secondary outcome measures were assessment of postoperative analgesic effect by Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) and time of first analgesic request. RESULTS: Our study showed that the mean total fentanyl consumption was comparable between both groups(38.67 ± 5.02 and 36.47 ± 5.13 µg in the E and QL groups, respectively, P = 0.246). Only five patients did not require rescue analgesia (3 in the E group,2 in the QL group, P = 0.378). The mean duration of analgesia showed no significant difference between the two groups (9.9 ± 1.58 and 11.02 ± 1.74 h in the E and QL groups, respectively, P = 0.212). Evaluation of CHEOPS score values immediately in PACU and for the initial 24 h following operation showed no significant difference between the two study groups(P > 0.05). CONCLUSION: QLB can achieve analgesic effects comparable to those of EB as a crucial part of multimodal analgesia in children undergoing abdominal surgeries. CLINICAL TRIAL REGISTRATION NUMBER: PACTR202203906027106.


Subject(s)
Abdomen , Abdominal Muscles , Nerve Block , Pain, Postoperative , Ultrasonography, Interventional , Humans , Male , Female , Nerve Block/methods , Ultrasonography, Interventional/methods , Pain, Postoperative/prevention & control , Child , Abdomen/surgery , Child, Preschool , Abdominal Muscles/diagnostic imaging , Anesthetics, Local/administration & dosage , Bupivacaine/administration & dosage , Analgesia, Epidural/methods , Fentanyl/administration & dosage , Analgesics, Opioid/administration & dosage
7.
Materials (Basel) ; 17(3)2024 Feb 05.
Article in English | MEDLINE | ID: mdl-38591985

ABSTRACT

Precision manufacturing requirements are the key to ensuring the quality and reliability of biomedical implants. The powder bed fusion (PBF) technique offers a promising solution, enabling the creation of complex, patient-specific implants with a high degree of precision. This technology is revolutionizing the biomedical industry, paving the way for a new era of personalized medicine. This review explores and details powder bed fusion 3D printing and its application in the biomedical field. It begins with an introduction to the powder bed fusion 3D-printing technology and its various classifications. Later, it analyzes the numerous fields in which powder bed fusion 3D printing has been successfully deployed where precision components are required, including the fabrication of personalized implants and scaffolds for tissue engineering. This review also discusses the potential advantages and limitations for using the powder bed fusion 3D-printing technology in terms of precision, customization, and cost effectiveness. In addition, it highlights the current challenges and prospects of the powder bed fusion 3D-printing technology. This work offers valuable insights for researchers engaged in the field, aiming to contribute to the advancement of the powder bed fusion 3D-printing technology in the context of precision manufacturing for biomedical applications.

8.
Materials (Basel) ; 17(2)2024 Jan 07.
Article in English | MEDLINE | ID: mdl-38255470

ABSTRACT

To address the weight, cost, and sustainability associated with fibreglass application in structural composites, plant fibres serve as an alternative to reduce and replace the usage of glass fibres. However, there remains a gap in the comprehensive research on plant fibre composites, particularly in their durability for viable structural applications. This research investigates the fatigue and impact properties of pultruded kenaf/glass-reinforced hybrid polyester composites tailored for structural applications. Utilising kenaf fibres in mat form, unidirectional E-glass fibre direct roving yarns, and unsaturated polyester resin as key constituents, pultruded kenaf/glass hybrid profiles were fabricated. The study reveals that pultruded WK/UG alternate specimens exhibit commendable fatigue properties (18,630 cycles at 60% ultimate tensile strength, UTS) and fracture energy (261.3 kJ/m2), showcasing promise for moderate load structural applications. Notably, the pultruded 3 WK/UG/3WK variant emerges as a viable contender for low-load structural tasks recorded satisfactory fatigue properties (10,730 cycles at 60% UTS) and fracture energy (167.09 kJ/m2). Fatigue failure modes indicate that the stress applied is evenly distributed. Ductile failures and delaminations during impact test can be attributed to damping and energy absorbing properties of kenaf fibres. Moreover, incorporating kenaf as a hybrid alternative demonstrates substantial reductions in cost (35.7-50%) and weight (9.6-19.1%). This research establishes a foundation for advancing sustainable and efficient structural materials and highlights the significant role of materials design in shaping the future of engineering applications.

9.
10.
Materials (Basel) ; 16(15)2023 Jul 27.
Article in English | MEDLINE | ID: mdl-37570000

ABSTRACT

Petrochemical plants use on-stream inspection often to detect and monitor the corrosion on the equipment and piping system. Compared to ultrasonic thickness gauging and pulse-echo A-scan, phased array corrosion mapping has better coverability and can scan a large area to detect general and localized corrosion. This paper's objective is to obtain documentary evidence for the accuracy of corrosion detection from 30 °C to 250 °C on A36 low-carbon steel by carrying out simulation experiments every 10 °C step. A minimum of three sets of phased array corrosion mapping data in each temperature were collected to study and evaluate the detectability. The data evidence could enhance the confidence level of the plant's end users in using phased array mapping in the future during inspections. The experiments were found to be insufficiently thorough despite addressing the initial concerns, leaving more area for discussion in further studies, such as expanding the investigation to thicker carbon steel, stainless steel, and wedge materials.

11.
Materials (Basel) ; 16(14)2023 Jul 20.
Article in English | MEDLINE | ID: mdl-37512396

ABSTRACT

On-stream inspections are the most appropriate method for routine inspections during plant operation without undergoing production downtime. Ultrasonic inspection, one of the on-stream inspection methods, faces challenges when performed at high temperatures exceeding the recommended 52 °C. This study aims to determine the ultrasonic velocity and attenuation with known material grade, thickness, and temperatures by comparing theoretical calculation and experimentation, with temperatures ranging between 30 °C to 250 °C on low-carbon steel, covering most petrochemical equipment material and working conditions. The aim of the theoretical analysis was to obtain Young's modulus, Poisson's ratio, and longitudinal velocity at different temperatures. The experiments validated the theoretical results of ultrasonic change due to temperature increase. It was found that the difference between the experiments and theoretical calculation is 3% at maximum. The experimental data of velocity and decibel change from the temperature range provide a reference for the future when dealing with unknown materials information on site that requires a quick corrosion status determination.

12.
Radiol Case Rep ; 18(8): 2836-2839, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37388266

ABSTRACT

Adult intussusception presents a diagnostic challenge given its non-specific symptoms. It is not as common as in infants and young children. Traditionally, diagnostic steps are invariably fit for normal adults, but not in pregnancy which faces certain limitations. A 40-year-old pregnant mother, gravida 9 para 8 at 34-week gestation, complained of intermittent epigastric pain for 2 days, requiring hospitalization. She soon developed minimal per rectal bleeding that was ruled out as hemorrhoid. Imaging was limited due to her pregnancy status. She later developed spontaneous delivery to a premature baby. Computed tomography (CT) revealed an ileocolic intussusception, which was confirmed via exploratory laparotomy. Histology was consistent with inflammatory fibroid polyp. Acute abdomen in pregnancy can be due to various causes, thus a high index of suspicion and early CT abdomen might help in early diagnosis and treatment. The benefit of doing CT on the mother and the risk of CT on the fetus is to be weighed as the timely diagnosis can prevent bowel ischemia and reduce maternal morbidity and mortality. Surgery remains the definite management in adult intussusception and an exact diagnosis can be made during the operation.

13.
Urol Ann ; 15(1): 88-94, 2023.
Article in English | MEDLINE | ID: mdl-37006212

ABSTRACT

Background: Transurethral resection of bladder tumors (TURBT) is the standard management for urinary bladder tumors; however, new techniques as Thulium laser en bloc resection of bladder tumors (TmLRBT) have been introduced as a substitute to TURBT. Objectives: In this study safety, efficacy, and tumor recurrence after TmLRBT and TURBT were prospectively compared in patients with primary (<4 cm) bladder tumors. Patients and Methods: Between August 2019 and May 2021, patients with primary (<4 cm) bladder tumors were enrolled. Patients were randomized between the two procedures. All perioperative data were collected prospectively. Pathological specimen findings and recurrence rates were reported during follow-up visits. Results: Sixty patients underwent TURBT, and another 60 had TmLRBT. No significant differences were detected in patient demographics or preoperative tumor characteristics between the two groups. Operation time was less (28.2 vs. 38.9 min, P < 0.001), and rate of bladder perforation was lower with TmLRBT compared to TURBT (3.3% vs. 15.0%, P = 0.027). In the TmLRBT group, higher rate of muscle detection (95.0% vs. 78.3%, P < 0.001) in the pathological specimen, and lower rate of tissue destruction (0.0% vs. 21.6%, P < 0.001) were obtained compared to TURBT. Recurrence rate in cases of nonmuscle invasive bladder cancer was lower with TmLRBT (6.7% vs. 33.0%, P < 0.001). Conclusion: In this study, TmLRBT showed reduced operative time with lower perforation rates. Higher detection of detrusor muscle and less tissue destruction in the pathological specimen were obtained with TmLRBT, as well as lower rates of tumor recurrence. These findings suggest that TmLRBT is a safe and efficacious substitute to TURBT in tumors <4 cm.

14.
Obes Surg ; 33(5): 1506-1518, 2023 05.
Article in English | MEDLINE | ID: mdl-36997694

ABSTRACT

PURPOSE: Obesity is associated with multiple health-related complications and affects various aspects of life, including erectile dysfunction (ED). The aim of this study is to postulate that erectile dysfunction in male obese patients can be reversed following bariatric surgery. MATERIALS AND METHODS: We conducted a non-randomized quasi-experimental study (prospective) between 2 groups, those who underwent surgery with the control group. In this study, the resolution of erectile dysfunction following bariatric surgery comparing with the control group was evaluated in terms of International Index of Erectile Function (IIEF) score. IIEF score is taken by delivering validated questionnaire to participants that enrolled in this study, both the control and intervention group. RESULTS: A total of 25 patients were included in this study, 13 from the intervention group and 12 from the control group. From our study, we evaluated the resolution of IIEF score in both groups. We found that the resolution of erectile function is statistically significant in the intervention group compared to control group. Spearman rank correlation (rs) test was performed to identify the correlation between age and IIEF score. CONCLUSION: Statistically significant improvements in erectile function were found following bariatric surgery. This is evidenced by the improvements in the IIEF score post-surgery compared to control group.


Subject(s)
Bariatric Surgery , Erectile Dysfunction , Obesity, Morbid , Male , Humans , Erectile Dysfunction/surgery , Erectile Dysfunction/complications , Prospective Studies , Obesity, Morbid/surgery , Obesity/complications , Obesity/surgery , Bariatric Surgery/adverse effects
15.
Environ Sci Pollut Res Int ; 30(18): 52514-52534, 2023 Apr.
Article in English | MEDLINE | ID: mdl-36829096

ABSTRACT

The past decade witnessed the initiation and boom of the Artisanal and Small-scale Gold Mining (ASGM) activities in the hyper-arid southern Egypt. The ores are mined in the Eastern Desert and then transported to the densely populated farming communities in the Nile Valley, where the river provides the water resources needed for ore processing. In search for economic benefits, the poorly educated farmers with limited technical resources transformed their cultivated lands into ASGM operations, exposing themselves, their families, the residents, and the Nile ecosystems to several environmental and occupational health problems. Using integrated remote sensing, field, geochemical, and isotopic analyses, we report the first inventory of ASGM-related total mercury (THg) and methylmercury (MeHg) levels in tailings, amalgamation-tailing ponds, and surface and groundwater with emphasis on the Edfu city and its surroundings. The field and remote sensing-based mapping of ASGM activities reveals clustering around the Nile waterways and suggests interaction of Hg contamination sources with their surrounding receptors. Common ASGM practices include release of contaminated water from unlined amalgamation-tailing ponds into irrigation and drainage canals, and spreading of tailings over cultivated soils. In a short period (10 years), the released Hg contaminated multiple media, including the surface water, the shallow and deep aquifers, and possibly the soil, crops, and livestock. THg levels in amalgamation-tailing ponds (1200-8470 ng/L) are fourfold higher than US EPA and eightfold the WHO thresholds. The contaminated waters released from amalgamation-tailing ponds raised THg levels in surface water (irrigation canals: 50-100 ng/L; drainage canals: THg: > 200 ng/L) and groundwater (shallow and deep aquifers: 80-500 ng/L). Our findings highlight the need to extend the adopted approach to cover the entire length of the Nile River and its valley and the importance of conducting awareness campaigns to educate residents and health care providers about potential ASGM-related environmental and health hazards.


Subject(s)
Mercury , Methylmercury Compounds , Humans , Mercury/analysis , Methylmercury Compounds/analysis , Ecosystem , Environmental Monitoring , Gold/analysis , Egypt , Soil , Mining , Water/analysis
16.
Turk J Surg ; 39(4): 377-382, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38694524

ABSTRACT

Adult idiopathic hypertrophic pyloric stenosis (AIHPS) is a rare entity first described by Cruveilhier in 1835. There are only approximately 200 cases reported in the English literature to date. Histologically, it may be mistaken for spindle cell neoplasms such as gastrointestinal stromal tumour (GIST). Patients with AIHPS usually present with early satiety, abdominal fullness, postprandial vomiting, epigastric pain, and eructations. Adult intussusception is rare and only accounts for 5% of all intussusceptions. Gastroduodenal intussusception is one of the rare types of adult intussusception. This is more likely to occur when a benign or malignant stomach lesion acts as a lead point. We report a case of AIHPS in a 70-year-old lady presenting with gastroduodenal intussusception. An oesophagogastroduodenoscopy (OGDS) was performed, and it revealed a diffusely thickened and narrowed pyloric antrum. A contrasted computed tomography (CECT) of the thorax and abdomen showed a distended stomach with circumferential thickening of the pylorus. The pre-pyloric antrum was intussuscepting into the pylorus, and the apex is seen within the first part of duodenum. She underwent distal gastrectomy with a Roux-en-y reconstruction via laparoscopic approach and was discharged well. AIHPS is a rare condition and should be a differential in adults presenting with gastric outlet obstruction. We believe in cases of AIHPS presenting with gastroduodenal intussusception, a distal gastrectomy with reconstruction is a reasonable approach. A multidisciplinary approach is essential to obtain the best outcome.

17.
Sci Rep ; 12(1): 22584, 2022 12 30.
Article in English | MEDLINE | ID: mdl-36585481

ABSTRACT

Numerous scientific, health care, and industrial applications are showing increasing interest in developing optical pH sensors with low-cost, high precision that cover a wide pH range. Although serious efforts, the development of high accuracy and cost-effectiveness, remains challenging. In this perspective, we present the implementation of the machine learning technique on the common pH paper for precise pH-value estimation. Further, we develop a simple, flexible, and free precise mobile application based on a machine learning algorithm to predict the accurate pH value of a solution using an available commercial pH paper. The common light conditions were studied under different light intensities of 350, 200, and 20 Lux. The models were trained using 2689 experimental values without a special instrument control. The pH range of 1: 14 is covered by an interval of ~ 0.1 pH value. The results show a significant relationship between pH values and both the red color and green color, in contrast to the poor correlation by the blue color. The K Neighbors Regressor model improves linearity and shows a significant coefficient of determination of 0.995 combined with the lowest errors. The free, publicly accessible online and mobile application was developed and enables the highly precise estimation of the pH value as a function of the RGB color code of typical pH paper. Our findings could replace higher expensive pH instruments using handheld pH detection, and an intelligent smartphone system for everyone, even the chef in the kitchen, without the need for additional costly and time-consuming experimental work.


Subject(s)
Mobile Applications , Smartphone , Algorithms , Machine Learning , Hydrogen-Ion Concentration
18.
BMC Vet Res ; 18(1): 387, 2022 Nov 03.
Article in English | MEDLINE | ID: mdl-36329452

ABSTRACT

BACKGROUND: Montmorillonite clay modified by organosulfur surfactants possesses high cation exchange capacity (CEC) and adsorption capacity than their unmodified form (UM), therefore they may elevate the adverse impact of aflatoxin B1 (AFB1) on ruminal fermentation and methanogenesis. Chemical and mechanical modifications were used to innovate the organically modified nano montmorillonite (MNM). The UM was modified using sodium dodecyl sulfate (SDS) and grounded to obtain the nanoscale particle size form. The dose-response effects of the MNM supplementation to a basal diet contaminated or not with AFB1 (20 ppb) were evaluated in vitro using the gas production (GP) system. The following treatments were tested: control (basal diet without supplementations), UM diet [UM supplemented at 5000 mg /kg dry matter (DM)], and MNM diets at low (500 mg/ kg DM) and high doses (1000 mg/ kg DM). RESULTS: Results of the Fourier Transform Infra-Red Spectroscopy analysis showed shifts of bands of the OH-group occurred from lower frequencies to higher frequencies in MNM, also an extra band at the lower frequency range only appeared in MNM compared to UM. Increasing the dose of the MNM resulted in linear and quadratic decreasing effects (P < 0.05) on GP and pH values. Diets supplemented with the low dose of MNM either with or without AFB1 supplementation resulted in lower (P = 0.015) methane (CH4) production, ruminal pH (P = 0.002), and ammonia concentration (P = 0.002) compared to the control with AFB1. Neither the treatments nor the AFB1 addition affected the organic matter or natural detergent fiber degradability. Contamination of AFB1 reduced (P = 0.032) CH4 production, while increased (P < 0.05) the ruminal pH and ammonia concentrations. Quadratic increases (P = 0.012) in total short-chain fatty acids and propionate by MNM supplementations were observed. CONCLUSION: These results highlighted the positive effects of MNM on reducing the adverse effects of AFB1 contaminated diets with a recommended dose of 500 mg/ kg DM under the conditions of this study.


Subject(s)
Aflatoxin B1 , Rumen , Animals , Aflatoxin B1/toxicity , Aflatoxin B1/analysis , Rumen/metabolism , Bentonite/pharmacology , Bentonite/analysis , Bentonite/metabolism , Ammonia/analysis , Surface-Active Agents/pharmacology , Fermentation , Diet/veterinary , Animal Feed/analysis , Digestion
19.
J Popul Ther Clin Pharmacol ; 29(3): e134-e156, 2022.
Article in English | MEDLINE | ID: mdl-36196948

ABSTRACT

Based on human capital theory, the goal of this study was to look into the role of innovation capabilities in the UAE healthcare sector's competitiveness. Following the qualitative research design, data were gathered through interviews with 90 experts and professionals working in the health industry in UAE. Furthermore, the study also analyzed the UAE's Human Development Index (HDI), innovation capacities, and human development competitiveness from 2014 to 2020 using the conceptual statistics of Key Performance Indicators (KPIs) obtained in the health sector. Results revealed that UAE achieved some positive indicator results from 2020 to 2021. In addition, there are significant areas of improvement through which the UAE can build a better rank in the global competitiveness index of the health sector. The study provided key policy insights for understanding the strengths and weaknesses of innovation capabilities and human development competitiveness in the healthcare sector. Avenues of growth policy and future research directions are suggested.


Subject(s)
Delivery of Health Care , Diffusion of Innovation , Humans , United Arab Emirates
20.
J Therm Anal Calorim ; 147(24): 14079-14096, 2022.
Article in English | MEDLINE | ID: mdl-36093037

ABSTRACT

Natural fibers have emerged as a potential alternate to synthetic fibers, because of their excellent performance, biodegradability, renewability and sustainability. This research has focused on investigating the thermal, visco-elastic and fire-retardant properties of different hybrid Cytostachys Renda (CR)/kenaf fiber (K) (50/0; 35/ 15, 25/25, 15/ 35, 0/50)-reinforced MWCNT (multi-walled carbon nanotubes)-modified phenolic composites. The mass% of MWCNT-modified phenolic resin was maintained 50 mass% including 0.5 mass% of MWCNT. In order to achieve homogeneous dispersion ball milling process was employed to incorporate the MWCNT into phenolic resin (powder). Thermal results from thermogravimetric analysis and differential scanning calorimetric analysis revealed that the hybrid composites (35/15; 35 mass% CR and 15 mass% K) showed higher thermal stability among the composite samples. Visco-elastic results revealed that kenaf fiber-based MWCNT-modified composites (0/50; 0 mass% CR and 50 mass% K) exhibited higher storage and loss modulus due to high modulus kenaf fiber. Fire-retardant analysis (UL-94) showed that all the composite samples met H-B self-extinguishing rating and exhibited slow burning rate according to limiting oxygen index (LOI) test. However, (15/35; 15 mass% CR and 35 mass% K) hybrid composites showed the highest time to ignition, highest fire performance index, lowest total heat release rate, average mass loss rate, average fire growth rate index and maximum average rate of heat emission. Moreover, the smoke density of all hybrid composites was found to be less than 200 which meets the federal aviation regulations (FAR) 25.853d standard. Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) was carried out to select an optimal composite sample considering the thermal, visco-elastic and fire-retardant behaviors. Through TOPSIS analysis, the hybrid (15/35; 15 mass% CR and 35 mass% K) composite sample has been selected as an optimal composite which can be used for high-temperature aircraft and automotive applications.

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