Subject(s)
Root Canal Irrigants/therapeutic use , Root Canal Therapy/methods , Chlorhexidine/therapeutic use , Citric Acid/therapeutic use , Dental Pulp Diseases/therapy , Edetic Acid/therapeutic use , Humans , Periapical Diseases/therapy , Root Canal Irrigants/classification , Sodium Hypochlorite/therapeutic useABSTRACT
Actinomycosis is considered to be a rare disease in the oral region. A retrospective study of files of the University of Nebraska Medical Center College of Dentistry, Department of Pathology, revealed 30 cases in which Actinomyces species were detected from the years 1982 to 2001 (28,490 specimens). Biopsy submission forms and patient records were reviewed in each of these cases with particular attention to clinical impression, subsequent treatment, and case outcome. Classic treatment for actinomycosis involves the excision of the affected area as well as long-term antibiotics. Our study indicates that antibiotics may not be necessary in treatment of the localized dental presentation of actinomycosis.
Subject(s)
Actinomycosis/epidemiology , Mandibular Diseases/microbiology , Maxillary Diseases/microbiology , Periapical Diseases/microbiology , Actinomyces/classification , Actinomyces/isolation & purification , Actinomycosis/drug therapy , Actinomycosis/physiopathology , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Biopsy , Curettage , Diagnosis, Differential , Female , Follow-Up Studies , Humans , Male , Mandibular Diseases/drug therapy , Mandibular Diseases/epidemiology , Maxillary Diseases/drug therapy , Maxillary Diseases/epidemiology , Middle Aged , Nebraska/epidemiology , Periapical Diseases/drug therapy , Periapical Diseases/epidemiology , Retrospective Studies , Treatment Outcome , Wound HealingABSTRACT
The purpose of this study was to determine the effect of one dose of a common narcotic-based pain reliever (Vicodin) on a battery of oral sensitivity tests across time in women. Fifteen Caucasian women randomly were given an oral dose of 10 mg of hydrocodone/1000 mg of acetaminophen or placebo in a double-blind, cross-over design. At baseline (before drug) and after 2, 4, and 8 h each subject was evaluated for sensitivity thresholds with four tests around an experimental tooth: (a) electric pulp tester applied to exposed root; (b) electric pulp tester on adjacent mucosa; (c) increasing probe pressure (grams) on adjacent mucosa; and (d) decreasing cold probe (degrees C) on the exposed root. The outcomes of all tests were not statistically different between drug and placebo treatments at any time point (p > 0.05). These results suggest that a systemic dose of hydrocodone/acetaminophen has little impact on healthy pulp or mucosa sensitivity in women as measured by common diagnostic tests.
