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Epidemiology ; 35(4): 512-516, 2024 Jul 01.
Article in English | MEDLINE | ID: mdl-38788149

ABSTRACT

Estimating the instantaneous reproduction number ( ) in near real time is crucial for monitoring and responding to epidemic outbreaks on a daily basis. However, such estimates often suffer from bias due to reporting delays inherent in surveillance systems. We propose a fast and flexible Bayesian methodology to overcome this challenge by estimating while taking into account reporting delays. Furthermore, the method naturally takes into account the uncertainty associated with the nowcasting of cases to get a valid uncertainty estimation of the nowcasted reproduction number. We evaluate the proposed methodology through a simulation study and apply it to COVID-19 incidence data in Belgium.


Subject(s)
Basic Reproduction Number , Bayes Theorem , COVID-19 , COVID-19/epidemiology , Humans , Belgium/epidemiology , Basic Reproduction Number/statistics & numerical data , Uncertainty , SARS-CoV-2 , Computer Simulation , Time Factors , Incidence
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