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1.
Diagnostics (Basel) ; 11(4)2021 Apr 20.
Article in English | MEDLINE | ID: mdl-33924146

ABSTRACT

Lung sounds remain vital in clinical diagnosis as they reveal associations with pulmonary pathologies. With COVID-19 spreading across the world, it has become more pressing for medical professionals to better leverage artificial intelligence for faster and more accurate lung auscultation. This research aims to propose a feature engineering process that extracts the dedicated features for the depthwise separable convolution neural network (DS-CNN) to classify lung sounds accurately and efficiently. We extracted a total of three features for the shrunk DS-CNN model: the short-time Fourier-transformed (STFT) feature, the Mel-frequency cepstrum coefficient (MFCC) feature, and the fused features of these two. We observed that while DS-CNN models trained on either the STFT or the MFCC feature achieved an accuracy of 82.27% and 73.02%, respectively, fusing both features led to a higher accuracy of 85.74%. In addition, our method achieved 16 times higher inference speed on an edge device and only 0.45% less accuracy than RespireNet. This finding indicates that the fusion of the STFT and MFCC features and DS-CNN would be a model design for lightweight edge devices to achieve accurate AI-aided detection of lung diseases.

2.
PLoS One ; 12(11): e0187603, 2017.
Article in English | MEDLINE | ID: mdl-29121100

ABSTRACT

The authors use four criteria to examine a novel community detection algorithm: (a) effectiveness in terms of producing high values of normalized mutual information (NMI) and modularity, using well-known social networks for testing; (b) examination, meaning the ability to examine mitigating resolution limit problems using NMI values and synthetic networks; (c) correctness, meaning the ability to identify useful community structure results in terms of NMI values and Lancichinetti-Fortunato-Radicchi (LFR) benchmark networks; and (d) scalability, or the ability to produce comparable modularity values with fast execution times when working with large-scale real-world networks. In addition to describing a simple hierarchical arc-merging (HAM) algorithm that uses network topology information, we introduce rule-based arc-merging strategies for identifying community structures. Five well-studied social network datasets and eight sets of LFR benchmark networks were employed to validate the correctness of a ground-truth community, eight large-scale real-world complex networks were used to measure its efficiency, and two synthetic networks were used to determine its susceptibility to two resolution limit problems. Our experimental results indicate that the proposed HAM algorithm exhibited satisfactory performance efficiency, and that HAM-identified and ground-truth communities were comparable in terms of social and LFR benchmark networks, while mitigating resolution limit problems.


Subject(s)
Algorithms , Models, Theoretical
3.
Cyberpsychol Behav ; 11(3): 293-301, 2008 Jun.
Article in English | MEDLINE | ID: mdl-18537499

ABSTRACT

In the latest versions of massively multiplayer online games (MMOGs), developers have purposefully made guilds part of game environments. Guilds represent a powerful method for giving players a sense of online community, but there is little quantitative data on guild dynamics. To address this topic, we took advantage of a feature found in one of today's most popular MMOGs (World of Warcraft) to collect in-game data: user interfaces that players can modify and refine. In addition to collecting data on in-game player activities, we used this feature to observe and investigate how players join and leave guilds. Data were analyzed for the purpose of identifying factors that propel game-world guild dynamics and evolution. After collecting data for 641,805 avatars on 62 Taiwanese World of Warcraft game servers between February 10 and April 10, 2006, we created five guild type categories (small, large, elite, newbie, and unstable) that have different meanings in terms of in-game group dynamics. By viewing players as the most important resource affecting guild life cycles, it is possible to analyze game worlds as ecosystems consisting of evolving guilds and to study how guild life cycles reflect game world characteristics.


Subject(s)
Internet , Social Identification , Software , User-Computer Interface , Video Games , Communication , Data Collection , Humans , Motivation , Social Environment , Taiwan
4.
IEEE Trans Syst Man Cybern B Cybern ; 38(1): 17-24, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18270079

ABSTRACT

A major task for postgenomic systems biology researchers is to systematically catalogue molecules and their interactions within living cells. Advancements in complex-network theory are being made toward uncovering organizing principles that govern cell formation and evolution, but we lack understanding of how molecules and their interactions determine how complex systems function. Molecular bridge motifs include isolated motifs that neither interact nor overlap with others, whereas brick motifs act as network foundations that play a central role in defining global topological organization. To emphasize their structural organizing and evolutionary characteristics, we define bridge motifs as consisting of weak links only and brick motifs as consisting of strong links only, then propose a method for performing two tasks simultaneously, which are as follows: 1) detecting global statistical features and local connection structures in biological networks and 2) locating functionally and statistically significant network motifs. To further understand the role of biological networks in system contexts, we examine functional and topological differences between bridge and brick motifs for predicting biological network behaviors and functions. After observing brick motif similarities between E. coli and S. cerevisiae, we note that bridge motifs differentiate C. elegans from Drosophila and sea urchin in three types of networks. Similarities (differences) in bridge and brick motifs imply similar (different) key circuit elements in the three organisms. We suggest that motif-content analyses can provide researchers with global and local data for real biological networks and assist in the search for either isolated or functionally and topologically overlapping motifs when investigating and comparing biological system functions and behaviors.


Subject(s)
Chromosome Mapping/methods , Databases, Protein , Models, Biological , Protein Interaction Mapping/methods , Proteome/metabolism , Signal Transduction/physiology , Computer Simulation , Models, Statistical , Systems Integration
5.
Artif Intell Med ; 41(2): 117-27, 2007 Oct.
Article in English | MEDLINE | ID: mdl-17825540

ABSTRACT

OBJECTIVE: A major focus in computational system biology research is defining organizing principles that govern complex biological network formation and evolution. The task is considered a major challenge because network behavior and function prediction requires the identification of functionally and statistically important motifs. Here we propose an algorithm for performing two tasks simultaneously: (a) detecting global statistical features and local connection structures in biological networks, and (b) locating functionally and statistically significant network motifs. METHODS AND MATERIAL: Two gene regulation networks were tested: the bacteria Escherichia coli and the yeast eukaryote Saccharomyces cerevisiae. To understand their structural organizing principles and evolutionary mechanisms, we defined bridge motifs as composed of weak links only or of at least one weak link and multiple strong links, and defined brick motifs as composed of strong links only. RESULTS: After examining functional and topological differences between bridge and brick motifs for predicting biological network behaviors and functions, we found that most genetic network motifs belong to the bridge category. This strongly suggests that the weak-tie links that provide unique paths for signal control significantly impact the signal processing function of transcription networks. CONCLUSIONS: Bridge and brick motif content analysis can provide researchers with global and local views of individual real networks and help them locate functionally and topologically overlapping or isolated motifs for purposes of investigating biological system functions, behaviors, and similarities.


Subject(s)
Algorithms , Computational Biology/methods , Databases, Genetic , Gene Regulatory Networks/genetics , Systems Biology/methods , Gene Expression Regulation/genetics , Neural Networks, Computer , Signal Transduction/genetics , Software , Transcription, Genetic/genetics
6.
Cyberpsychol Behav ; 9(5): 560-70, 2006 Oct.
Article in English | MEDLINE | ID: mdl-17034323

ABSTRACT

The aim of this study was to look at motivations behind altruistic behavior in virtual communities by studying the sharing of game tips by experienced gamers. We examine several possible motivations (pure altruism, generalized reciprocity, and reputation) and qualitatively analyze tip types in terms of usefulness, visibility, and skill level. We found that in games that do not support a "performance stage" for skill demonstration, players often share game tips as a strategy to attract attention. To a certain degree, reciprocity can be used to explain small favor exchanges, but earning social reputation is often a much stronger motivating factor.


Subject(s)
Communication , Helping Behavior , Internet , Interpersonal Relations , Motivation , Video Games/psychology , Adult , Altruism , Humans , Male , Reinforcement, Social , Role Playing , Self-Assessment , Social Dominance , Taiwan
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