1.
Org Lett
; 25(43): 7816-7821, 2023 Nov 03.
Article
in English
| MEDLINE
| ID: mdl-37870311
ABSTRACT
An electrochemical strategy for the decarboxylative elimination of carboxylic acids to alkenes at room temperature has been developed. This mild and oxidant-free method provides a green alternative to traditional thermal decarboxylation reactions. Structurally diverse aliphatic carboxylic acids, including biologically active drugs, underwent smooth conversion to the corresponding alkenes in good to excellent yields.