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1.
Diagn Cytopathol ; 51(7): 455-464, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37154168

ABSTRACT

Endoscopic ultrasound enables visualization of lesions within and in the vicinity of the gastrointestinal tract. Endoscopic ultrasound guided fine needle aspiration cytology (EUS-FNAC) helps in targeting various luminal and extraluminal lesions both diagnostically and therapeutically. Various intra-abdominal organs amenable to EUS-FNA include the gastrointestinal tract (GIT), pancreas, kidney, adrenal gland, liver, bile duct, gallbladder, spleen, and lymph nodes. EUS-FNAC is mostly done for pancreatic and intra-abdominal lymph nodal lesions. In the present review, we have discussed various aspects of EUS-FNAC.


Subject(s)
Endoscopic Ultrasound-Guided Fine Needle Aspiration , Pancreatic Neoplasms , Humans , Endoscopic Ultrasound-Guided Fine Needle Aspiration/methods , Endosonography , Lymph Nodes/pathology , Abdomen/diagnostic imaging , Abdomen/pathology , Pancreas/diagnostic imaging , Pancreas/pathology , Pancreatic Neoplasms/pathology
3.
Diagn Cytopathol ; 49(4): E167-E171, 2021 Apr.
Article in English | MEDLINE | ID: mdl-33002340

ABSTRACT

BACKGROUND: Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder of B cell origin, and uncommonly it affects the lymph node. Fine needle aspiration cytology (FNAC) of lymph node of HCL has rarely been described. CASE DESCRIPTION AND DIAGNOSIS: A 41-year-old man presented with pallor, fever, tachycardia, generalized lymphadenopathy, and massive splenomegaly. The FNAC of the cervical lymph node was done. The smears showed many atypical lymphocytes with a plasmacytoid appearance. There were many large cells with round to reniform shaped nuclei having with hair-like cytoplasmic processes. Flow cytometry (FCM) revealed a clonal B cell population with light chain restriction and positive CD20, CD79b, CD22, CD11c, CD25, CD103, CD123, and CD200 markers. CONCLUSION: The characteristic cytological features such as atypical lymphoid cells, large cells with hairy projections along with FCM findings, are helpful in the diagnosis of HCL.


Subject(s)
Leukemia, Hairy Cell/pathology , Lymph Nodes/pathology , Adult , Antigens, CD/metabolism , B-Lymphocytes/metabolism , B-Lymphocytes/pathology , Biopsy, Fine-Needle/methods , Flow Cytometry/methods , Humans , Male
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