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Epidemiol Infect ; 146(11): 1359-1365, 2018 08.
Article in English | MEDLINE | ID: mdl-29898797

ABSTRACT

The Arizona Department of Health Services identified unusually high levels of influenza activity and severe complications during the 2015-2016 influenza season leading to concerns about potential increased disease severity compared with prior seasons. We estimated state-level burden and severity to compare across three seasons using multiple data sources for community-level illness, hospitalisation and death. Severity ratios were calculated as the number of hospitalisations or deaths per community case. Community influenza-like illness rates, hospitalisation rates and mortality rates in 2015-2016 were higher than the previous two seasons. However, ratios of severe disease to community illness were similar. Arizona experienced overall increased disease burden in 2015-2016, but not increased severity compared with prior seasons. Timely estimates of state-specific burden and severity are potentially feasible and may provide important information during seemingly unusual influenza seasons or pandemic situations.


Subject(s)
Influenza A Virus, H1N1 Subtype , Influenza, Human/epidemiology , Adolescent , Adult , Aged , Arizona/epidemiology , Child , Child, Preschool , Cost of Illness , Hospitalization/statistics & numerical data , Humans , Influenza, Human/mortality , Middle Aged , Monte Carlo Method , Pneumonia/epidemiology , Pneumonia/mortality , Severity of Illness Index , Young Adult
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