ABSTRACT
Paecilomyces is a colonizing fungal species which usually causes keratitis, endocarditis, sinusitis, nephritis, fungemia, cutaneous, and subcutaneous infections in immunocompromised host. Very rarely, it causes similar infection in immunocompetent host without any risk factors. We report a case of maxillary sinusitis due to Paecilomyces lilacinus in a 65-year-old immunocompetent male, who presented with a subcutaneous swelling below the left eye. The lesion was excised by surgery and treated with itraconazole for 6 months based on culture and sensitivity. After 1 year of follow up, he is free of symptoms with no evidence of recurrence.
ABSTRACT
Giant cell tumor of the skin is a rare entity showing gross and histological features similar to those of giant cell tumor of the bone. We report a case of malignant giant cell tumor of the thigh in a 55-year-old man. Histological features showed a biphasic population of mononuclear cells admixed with osteoclast-like giant cells. The nuclei of the giant cells were similar to those of the mononuclear cells. This tumor should be distinguished from a variety of cutaneous neoplasms that contain multinucleated giant cells.
