Simulating transport, flux, and ecological risk of perfluorooctanoate in a river affected by a major fluorochemical manufacturer in northern China.

Perfluoroalkyl acids (PFAAs) have been widely detected and pose potential risks to both human and ecosystem health. Since the probation of perfluorooctane sulfonate (PFOS) by the Stockholm Convention, perfluorooctanoate (PFOA) has frequently been used as a chemical intermediate and processing aid. Owing to a lack of effective treatment technologies for PFOA, surrounding environments have been highly affected. Previous studies by our group have reported elevated PFOA levels in the Xiaoqing River, which receives sewage from a major fluorochemical manufacturer in northern China. To further explore the transport, flux, and ecological risk of the perfluorooctanoate in the river, this study conducted a 2-year sampling campaign of surface water from 2014 to 2015. An extremely high PFOA concentration (mean: 62.3 µg L-1) was observed for the Xiaoqing River in comparison with other studies. The highest average concentration and flux of PFOA were recorded in the autumn and summer, respectively. With data on selected hydrological parameters and cross-sections, PFOA concentrations were modeled using DHI MIKE 11. To explore the current loads and environmental capacity of PFOA, two scenarios (i.e., emissions based on observed concentrations and on the predicted no-effects concentration, PNEC) were set. The simulation results based on observed data showed that PFOA loads in the Xiaoqing River were 11.4 t in 2014, and 12.5 t in 2015. Based on the PNEC, the environmental carrying capacity of PFOA was estimated to be 13.9 t in 2014, and 13.8 t in 2015. The current loads of PFOA were found to approach the maximum environmental carrying capacity. Relatively high risks around both the fluorine industrial park (FIP) and estuary area were identified. In comparison with other suggested guidelines, threats to the ecological status of the river would be severe, which suggests that stringent management and emission criteria are needed for this industry.

Risk ranking of environmental contaminants in Xiaoqing River, a heavily polluted river along urbanizing Bohai Rim.

Xiaoqing River, located in the Laizhou Bay of Bohai Sea, is heavily polluted by various pollutants including heavy metals, polycyclic aromatic hydrocarbons (PAHs), hexachlorocyclohexanes (HCHs), perfluoroalkyl acids (PFAAs), bisphenol A (BPA) and pharmaceutical and personal care products (PPCPs). The aim of this study is to identify the relative risks of such contaminants that currently affect the coastal ecosystem. The median and highest concentrations of PFAAs and perfluorooctanoic acid (PFOA) were 3.23 µg L-1 and 325.28 µg L-1, and 0.173 µg L-1 and 276.24 µg L-1, respectively, which were ranked higher when compared with global level concentrations. To assess the relative risk levels of perfluorooctane sulfonic acid (PFOS), PFOA, and other contaminants in the upstream and downstream of the Xiaoqing River and in its tributary, a risk ranking analysis was carried out. Copper (Cu), Zinc (Zn), and arsenic (As) showed the highest risk values in the Xiaoqing River, while the relative risks of PFOA and PFOS differed across the various segments. The risk ranking of PFOA was the second highest in the tributary and the fourth highest in the downstream portion of the river, whereas the PFOS was found to be the lowest in all the segments. Heavy metals and PFOA are the main chemicals that should be controlled in the Xiaoqing River. The results of the present study provide a better understanding of the potential ecological risks of the contaminants in Xiaoqing River.

Distribution, source, and risk of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in urban and rural soils around the Yellow and Bohai Seas, China.

Between 1945 and 1983, China was the world's largest producer of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), and the second largest producer of hexachlorocyclohexanes (HCHs) and dichlorodiphenyltrichloroethanes (DDTs). The provinces of Liaoning, Hebei, Tianjin, Shandong, and Jiangsu around the Yellow and Bohai Seas have a long history of production and usage of OCPs and PCBs. To investigate their residual concentration, distribution, risk level, and temporal degradation, 7 OCPs and 7 indicator PCBs were determined in surface soils collected around the Yellow and Bohai Seas. Residues of the 7 OCPs and 7 PCBs were in the range of 5.89-179.96 ng g-1 dry weight (dw) and non-detectable (ND)-385.67 ng g-1 dw, respectively. Tianjin and Hebei provinces recorded the highest concentrations of OCPs and PCBs, respectively. Moreover, OCPs residues had a significant relationship with agriculture and orchard land-use types, whereas PCBs residues occurred more in wasteland. Lifetime carcinogenic and non-carcinogenic risks of OCPs and PCBs through ingestion, inhalation, and dermal contact indicated that OCPs and PCBs residues in surface soils are at a low risk level.

Response of the phytoplankton community to water quality in a local alpine glacial lake of Xinjiang Tianchi, China: potential drivers and management implications.

Eutrophication has become one of the most serious threats to aquatic ecosystems in the world. With the combined drivers of climate change and human activities, eutrophication has expanded from warm shallow lakes to cold-water lakes in relatively high latitude regions and has raised greater concerns over lake aquatic ecosystem health. A two-year field study was carried out to investigate water quality, phytoplankton characteristics and eutrophication status in a typical alpine glacial lake of Tianchi, a scenic area and an important drinking water source in the Xinjiang Autonomous Region of China, in 2014 and 2015. Clear seasonal and annual variations of nutrients and organic pollutants were found especially during rainy seasons. For the phytoplankton community, Bacillariophyta held the dominant position in terms of both species and biomass throughout the year, suggesting the dominant characteristics of diatoms in the phytoplankton structure in such a high-altitude cold-water lake. This was quite different from plain and warm lakes troubled with cyanobacterial blooming. Moreover, the dominant abundance of Cyclotella sp. in Tianchi might suggest regional warming caused by climate change, which might have profound effects on the local ecosystems and hydrological cycle. Based on water quality parameters, a comprehensive trophic level index TLI (Σ) was calculated to estimate the current status of eutrophication, and the results inferred emerging eutrophication in Tianchi. Results from Canonical Correspondence Analysis (CCA) and correlation analysis of phytoplankton genera and physico-chemical variables of water indicated that abiotic factors significantly influenced the phytoplankton community and its succession in Tianchi Lake. These abiotic factors could explain 77.82% of the total variance, and ammonium was identified as the most discriminant variable, which could explain 41% of the total variance followed by TP (29%). An estimation of annual nutrient loadings to Tianchi was made, and the results indicated that about 212.97 t of total nitrogen and 32.14 t of total phosphorus were transported into Tianchi Lake annually. Human socio-economic activities (runoff caused by historical overgrazing and increasing tourism) were identified as the most important contributors to Tianchi nutrient loadings.

Using hydrodynamic model to predict PFOS and PFOA transport in the Daling River and its tributary, a heavily polluted river into the Bohai Sea, China.

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are extremely persistent in the environment, and have the potential for long-range transport. The present study focused on the Daling River and its tributary, a larger river flowing into Liaodong Bay of the Bohai Sea. Recent studies have shown the elevated levels of PFOS and PFOA in the Daling River. Hence, the objective of this study was to investigate the seasonal changes, fate and transport modeling of PFOS and PFOA concentrations using one-dimensional DHI MIKE-11 river model. We designed three scenarios to assess the risk of PFOS and PFOA in surface water: the measured concentrations, constant maximum and the magnitude of a continuous constant load. The mean absolute errors divided by the mean of measured concentrations were 41-64% for PFOS and 29-36% for PFOA. The result indicated that PFOS and PFOA in the downstream of the Daling River would not reach a harmful level with the current load. The fluorochemical parks contributed an average of 44.57% of the total PFOS and 95.44% of the total PFOA flow that reached the estuary. The mass flow was observed as 1.74 kg y-1 for PFOS and 40.57 kg y-1 for PFOA to the Bohai Sea. These modeling results may be useful for monitoring the status and trends of emerging POPs and will help the determination of the risk to both humans and wildlife, in the estuarine and coastal areas of the Bohai Sea, China.

Potential in vitro antioxidant and protective effects of Gymnema montanum H. on alloxan-induced oxidative damage in pancreatic beta-cells, HIT-T15.

The present study describes the antioxidant activities of ethanol extract from Gymnema montanum (GLEt) which is an endemic plant of India. Antioxidant activity of the GLEt was studied in vitro based on scavenging of hydroxyl radicals, superoxide anions, nitric oxide, hydrogen peroxide, peroxynitrite, reducing power and inhibition of lipid peroxidation estimated in terms of thiobarbituric acid reactive substances (TBARS). Further, we examined its protective effect against alloxan-induced oxidative stress in pancreatic beta-cells, HIT-T15 by measuring the free radical generation, malonaldehyde formation and antioxidant levels such as CAT, GPx and GSH. Results showed that G. montanum leaves exhibited significant antioxidant activities measured by various in vitro model systems. The HIT-T15 cell line studies showed the tendency of GLEt to increase antioxidant levels meanwhile decrease the free radical formation and inhibit the lipid peroxidation. The antioxidant activity was found to be well correlated with the phenolic phytochemicals present in the extract. GC-MS analyses revealed the presence of few phenolic compounds in the extract. As this plant has already been demonstrated for a variety of medicinal properties from our laboratory, results of this study suggest that G. montanum is an interesting source for antioxidant compounds and useful for various therapeutic applications.