ABSTRACT
OBJECTIVES: Neurenteric cysts (NCs) of the central nervous system (CNS) are cystic congenital lesions that may occur anywhere along the neural tube. They are most common in the spinal region, in the lower part of the cervical and upper thoracic spine. Intracranial NCs occur rarely and there are only small series of patients published in literature worldwide. Microsurgical resection is the treatment of choice. We present our experience in treatment of NCs and review of literature. METHODS: Seven patients with NC of CNS who were operated at the Department of Neurosurgery of Comenius University at University Hospital Bratislava within nine years (2010-2018) were included in the study. The series was retrospectively evaluated with an emphasis on symptomatology, surgery and postoperative course. RESULTS: In three of the seven patients, NC was localized intracranially, in the other four, NC was in the spinal canal. In three patients, a complete removal of NC was achieved (2 intracranial NC, 1 spinal NC). In other patients, a portion of the cyst wall was left to prevent the development of a postoperative neurological deficit. After surgery, the neurological symptoms were completely resolved in six patients, while in one patient, they were alleviated. In one patient, a complication occurred during the postoperatove course. There was no recurrence during the follow-up (3-111 months, mean duration 39 months). CONCLUSION: In our series of patients with intracranial and intraspinal tumors, the incidence of NC was higher than presented in the published data. Our own surgical experience has shown that complete tumor resection is not always possible for intimate adherence to the surrounding structures. Leaving a tiny portion of the cyst wall allowed us to achieve good clinical results with no recurrence. Long-term follow-up of patients is required due to the risk of recurrence. However, it can already be stated that an adequate extent of resection leads to good clinical results (Tab. 1, Fig. 4, Ref. 33).
Subject(s)
Neural Tube Defects/epidemiology , Neural Tube Defects/surgery , Humans , Incidence , Neurosurgical Procedures , Retrospective StudiesABSTRACT
The authors present their experience with microsurgical replacement of brainstem lesions within the period 1989-1999. They operated on 35 patients with tumors and with KM? at age ranging from 2 to 65 years. The children suffered prevailingly from gliomas. KM was more frequent in adults. Ten adults were treated for tumors (4 gliomas, 3 haemangioblastomas, 2 primary lymphomas and 1 epidermoid). A correct surgical technique by use of microsurgical technology can replace relatively safely replace the tumor and vascular lesions even from the inside of the brainstem.
Subject(s)
Brain Stem Neoplasms/surgery , Central Nervous System Vascular Malformations/surgery , Hemangioma, Cavernous/surgery , Adolescent , Adult , Brain Stem/blood supply , Child , Child, Preschool , Humans , Infant , Microsurgery , Middle AgedABSTRACT
Clivus meningeoma is a relatively rare tumor with difficult surgical accession. Large and giant tumors acquire a very close relation to the brain stem, cranial nerves and brain vessels. In 10 our of 13 patients, the large tumor diameter exceeded 4 cm, and in half of them it was larger than 5 cm (max. 6.5 cm). Small and medium-sized tumors were removed by means of simple neurosurgical approaches. All of the 10 large and giant tumors were removed by a combined supra-infratentorial presigmoid approach which enabled the approach to the whole tumor. Three recurrent tumors were removed subtotally, the primary surgical intervention removed 5 tumors radically, 4 subtotally and 1 partially. The entire removal was precluded due to infiltrative growth of the tumor localized in the cavernous sinus, firm adherence of tumor to the brain stem or to the vertebrobasillar vessels. Authors' own experience support the data from literature dealing with the relationship of unfavourable results to the size of tumor. Permanent impairment of cranial nerves (38.5%) occurred mostly in large and giant tumors. One death (7.7%) during the peri-operative period (up to one month following operation), as well as the second that occurred in later period succeeded the removal of a giant tumor. Regarding the character of the relationship of large clivus meningeoma to the surrounding nerve and vascular structures, the future improvement of functional results can be expected especially owing to early diagnosis. (Tab. 2, Fig. 2, Ref. 19.)
