1.
ACS Omega
; 3(12): 18065-18077, 2018 Dec 31.
Article
in English
| MEDLINE
| ID: mdl-31458393
ABSTRACT
The use of liquid sulfur dioxide as a reaction solvent to promote chemical transformations of alkynes has been explored. First, a combination of liquid SO2 and In(OTf)3 or Hf(OTf)4 as a catalyst allows to perform hydration of aryl alkynes under mild conditions without a direct addition of Brønsted acid. Second, novel catalyst-free conditions for the synthesis of α-vinyl iodides, bromides, and chlorides from aryl alkynes have been developed in liquid SO2 using group I and II metal halides and ammonium iodide as the halide ion sources.