[Clinical monitoring in areas of exposure to radiofrequency electromagnetic fields].

Clinical syndromes induced by high intensity radiofrequency electromagnetic field chronic exposure are described. Persons injured by occupational exposure have been observed central nervous system changes in diencephalic syndrome form, cardio-vascular system changes revealed in atherosclerosis, isch(a)emic heart disease and coronary insufficiency rapid progressive expansion. General public living in territory of radar station exposure zone different functional disorders have been identified: vegetative dystonia (asthenovegetative syndrome), thrombocytopenia, decrease of blood coagulation index, and thyroid gland function changes. Observed diseases clinical variability may be determined by electromagnetic exposure characteristics.

[Variability of heart rhythm in patients with vibration disease caused by local vibration]. / Variabel'nost' serdechnogo ritma u bol'nykh vibratsionnoi bolezn'iu ot vozdeistviia lokal'noi vibratsii.

The authors revealed a dependence of disordered autonomous regulation of cardiac rhythm on vibration disease severity, local vibration and on length of service with exposure to vibration.

[Some aspects of pathogenesis, clinical manifestations and diagnosis of occupational chronic occupational bronchitis]. / Nekotorye aspekty patogeneza, kliniki i diagnostiki khronicheskikh bronkhitov professional'noi étiologii.

The article represents data characterizing course of chronic bronchitis in 78 machinery workers subjected to toxic irritative and sensibilizing aerosols. Findings are early bronchial obstruction and pulmonary emphysema, frequent disorders of microcirculation and lesser circle perfusion, propensity to interstitial pulmonary fibrosis and lung hypertension. The results could serve as a base for pathogenetic therapy and necessitate to include COLD into Occupational Diseases Register.

[The pathogenesis, clinical picture and treatment of poisonings by organic solvents, derivatives of chlorinated hydrocarbons (trichloroethylene, carbon tetrachloride)]. / Patogenez, klinika i lechenie otravlenii nekotorymi organicheskimi rastvoriteliami, proizvodnymi khlorirovannykh uglevodorov (trikhlorétilen, chetyrekhkhloristyi uglerod).

Clinical studies and experiments on laboratory animals covered mechanism of trichloroethylene toxicity. The chemical and its metabolites cause nonspecific toxic effects in membranes and therefore induce energy metabolism disorder that is proved to be a trigger of pathologic process in the intoxication. Experimental studies failed to disclose and explain mechanism of compromised calcium metabolism and its role in cardiac manifestations seen in trichloroethylene poisoning.

[The pathogenesis of trichloroethylene poisoning]. / O patogeneze trikhlorétilenovoi intoksikatsii.

Basing on the results of original clinical and experimental studies, as well as on medical literature data, the contributors proposed a hypothesis of the toxic action of trichloroethylene. It was attempted to prove that the trigger links of trichloroethylene intoxications were the energy exchange disorders caused by the nonspecific membranotoxic actions of the substance's molecules and their metabolites, as well as the extra consumption of energy by the metabolic processing of the poison. Involvement of adaptational reactions, such as the catecholamines' discharge, under the conditions of the damaged metabolic system, decreased the cell's potential and aggravated the severity of intoxications.

[A case of mass legionellosis infection in an enterprise of the rubber technology industry]. / Sluchai massovogo zabolevaniia legionellezom na predpriiatii rezinotekhnicheskoi promyshlennosti.

On the basis of the analysis of the sanitary and hygienic conditions, epidemiology of a mass disease, clinical picture of the disease during a 6-month trial period the problems of differentiated diagnosis of infectious and toxic processes, examination of capacity for work, the course of diseases were studied in 219 workers who had had legionellosis. The participation of various specialists in the analysis of analogous cases at the enterprises with chemical environmental contamination and developed systems of air conditioning was considered necessary.

[Acute occupational poisonings]. / K voprosu ob ostrykh professional'nykh otravleniiakh.

The contributors provide an analysis of acute occupational poisoning cases basing on the data obtained by the Institute of Occupational Diseases in Leningrad for 1980-1987, investigate the structure of the registered acute poisonings, their occurrence and reasons. A more detailed clinical description of an acute poisoning with trichlorethylene is given with particular emphasis on its cardiotoxic effects.

[Clinical variants of the disease caused by exposure to radio-frequency electromagnetic fields]. / Klinicheskie varianty zabolevaniia, vyzyvaemogo vozdeitsviem élektromagnitnykh polei radiochastot.

Clinical data on the characteristics of the course of the disease caused by microwave radiation are presented. It is assumed that the characteristics of the clinical picture of the disease are specified by radiation "geometry".

[Pathogenetic therapy of cobalt-induced cardiomyopathies]. / Patogeneticheskaia terapiia kobal'tovykh kardiomiopatii.

The pathogenesis of damage to the heart muscle caused by exposure to the effect of cobalt compounds is demonstrated. Agents with various mechanisms of action were tested in the experiment. The most effective pharmacological agents (beta-adrenergic blocking agents, anabolic steroids) are recommended for testing in the clinic. A positive effect was registered in the treatment of cobalt cardiomyopathy in the clinic. The mechanisms of the favourable effect of beta-adrenergic blocking agents and anabolic steroids are discussed.