ABSTRACT
BACKGROUND: Human immunodeficiency virus (HIV) is a pandemic disease affecting all regions across the globe and Nigeria having the second highest prevalence worldwide. Highly active antiretroviral therapy (HAART) has profound negative effect on the optic nerve even though (HAART) has improved the health status of the affected individuals and overall reduction in mortality. Imaging modality especially ultrasound has a great role in the assessment of the optic nerve because of its availability, affordability, and easy operability with reliable sensitivity. SUBJECTS AND METHODS: This cross-sectional study was conducted at the Department of Radiology and Ophthalmology, AKTH, Kano, from October 2017 to June 2018. A total of 143 consenting HIV-positive adults age 18-60 years on HAART were recruited. Optic nerve sheath diameter (ONSD) of each eye was measured using 11-14 MHz linear transducer. Ethical approval was obtained from the ethic and research committee of the hospital. RESULTS: The mean ONSD value of the right eye was 3.49 mm ± 1.04 standard deviation (SD) and 3.55 mm ± 1.11 SD for the left eye. The optic nerve diameter was found to be larger on the left eye and increased slightly with age (P < 0.05). There was nonsignificantly higher values of ONSD among female (3.59 mm ± 1.12 SD) when compared with males (3.332 mm ± 0.878) with P value >0.005. CONCLUSION: ONSD values among HIV-positive patients are significantly higher in the left eye and among female subjects. Also, patients with HIV on HAART have thicker optic nerves when compared with general population in Kano, Nigeria.
Subject(s)
HIV Infections/complications , Optic Nerve/diagnostic imaging , Ultrasonography/methods , Adult , Antiretroviral Therapy, Highly Active , Cross-Sectional Studies , Female , HIV Infections/drug therapy , Health Status , Humans , Male , Middle Aged , Nigeria , Young AdultABSTRACT
BACKGROUND: Magnetic resonance imaging (MRI) of the spine is a powerful tool for evaluation, assessment of severity, and follow up of diseases of the spine. It is one of the most sensitive diagnostic tests for detecting anatomic abnormalities of the spine and the adjacent structures. AIM: To determine the pattern of spinal abnormalities on MRI in Kano, Nigeria. MATERIALS AND METHOD: Patients aged between 2 and 95 years who had spinal MRI with AIRIS II TOSHIBA (0.5T) Tesla machine from January to December 2013 were reviewed. Information concerning age, gender, region and findings were recorded. RESULTS: Two hundred and sixty one patients made up of187 males and 74 females were reviewed. Their ages ranged from 2 to 95 years with the mean of 46.43 ± 15.7 years. Lumbo-sacral MRI was the most commonly performed (46.4 %) followed by cervical (44.1%), thoraco-lumbar spine (4.2%), thoracic spine (3.8%) and cervical and lumbar (1.5%). The most common indication of MRI was low back pain in 211 (80.8% ) patients followed by trauma in 36 (17.8% ) patients. About 19.6% of the MRI examinations were normal while spondylosis and moderate disc prolapse was seen in 31.5% and compressive fracture comprised 7.3% of cases. CONCLUSION: Lumbo-sacral MRI was the commonest MRI in this study and the commonest indications for MRI were low back pain and trauma while the commonest findings were spondylosis, disc prolapse, compressive fracture and spinal metastases.
