ABSTRACT
Novel heterocyclic quinol-type fluorophores (4 a-c) and (5 a-c) that contain substituents (R = Me, Bu, Ph) with nonconjugated linkages to the chromophore skeleton have been synthesized and their photophysical properties have been investigated in solution and in the solid state. Considerable differences in the absorption and fluorescence spectra were observed between the two states. Quinols 4 a-c and 5 a-c exhibited almost the same absorption and fluorescence spectra in solution; however, their solid-state fluorescence excitation and emission spectra in the crystalline state were quite different. We performed X-ray crystallographic analyses to elucidate the dramatic effect of the substituents of the nonconjugated linkage on the solid-state fluorescence excitation and emission spectra. The relationships between the solid-state photophysical properties and the chemical and crystal structures of 4 a-c and 5 a-c are discussed on the basis of the X-ray crystal structures.
ABSTRACT
We report a rare case of a spontaneous umbilical fistula as a complication of ventriculo-peritoneal shunt. A 36 year-old male was admitted our hospital complaining serous discharge from the umbilicus. Two years before admission, he underwent ventriculo-peritoneal shunt for the hydrocephalus due to right hypertensive intracranial hematoma and intraventricular hemorrhage. A shuntgraphy was done and it revealed the cerebrospinal fluid leakage from the umbilicus through an urachal remnant. The abdominal shunt tube was removed at the surgery, and the patient was discharged uneventfully without shunt revision. The possible etiology of this rare complication in this case was supposed to be due to the persistence of the urachus.
