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1.
Lakartidningen ; 1192022 09 14.
Article in Swedish | MEDLINE | ID: mdl-36106736

ABSTRACT

In patients with coronary artery disease, exercise-based cardiac rehabilitation (EBCR) is recommended to decrease all-cause and cardiovascular mortality, hospitalisation and risk of myocardial infarction and to improve aerobic capacity and muscle strength and endurance. Before starting the EBCR program, a pre-exercise screening is conducted. Exercise is individually prescribed based on tests of aerobic and muscular strength/endurance, as part of a comprehensive and medically supervised program. A post-exercise assessment is performed to evaluate the effects of exercise and to provide an exercise prescription to encourage life-long exercise.


Subject(s)
Cardiac Rehabilitation , Coronary Artery Disease , Myocardial Infarction , Exercise/physiology , Exercise Therapy , Humans , Myocardial Infarction/prevention & control
2.
Eur Heart J Acute Cardiovasc Care ; 11(2): 89-98, 2022 Feb 08.
Article in English | MEDLINE | ID: mdl-34905049

ABSTRACT

AIMS: Data on the prognostic value of frailty to guide clinical decision-making for patients with myocardial infarction (MI) are scarce. To analyse the association between frailty classification, treatment patterns, in-hospital outcomes, and 6-month mortality in a large population of patients with MI. METHODS AND RESULTS: An observational, multicentre study with a retrospective analysis of prospectively collected data using the SWEDEHEART registry. In total, 3381 MI patients with a level of frailty assessed using the Clinical Frailty Scale (CFS-9) were included. Of these patients, 2509 (74.2%) were classified as non-vulnerable non-frail (CFS 1-3), 446 (13.2%) were vulnerable non-frail (CFS 4), and 426 (12.6%) were frail (CFS 5-9). Frailty and non-frail vulnerability were associated with worse in-hospital outcomes compared with non-frailty, i.e. higher rates of mortality (13.4% vs. 4.0% vs. 1.8%), cardiogenic shock (4.7% vs. 2.5% vs. 1.9%), and major bleeding (4.5% vs. 2.7% vs. 1.1%) (all P < 0.001), and less frequent use of evidence-based therapies. In Cox regression analyses, frailty was strongly and independently associated with 6-month mortality compared with non-frailty, after adjustment for age, sex, the GRACE risk score components, and other potential risk factors [hazard ratio (HR) 3.32, 95% confidence interval (CI) 2.30-4.79]. A similar pattern was seen for vulnerable non-frail patients (fully adjusted HR 2.07, 95% CI 1.41-3.02). CONCLUSION: Frailty assessed with the CFS was independently and strongly associated with all-cause 6-month mortality, also after comprehensive adjustment for baseline differences in other risk factors. Similarly, non-frail vulnerability was independently associated with higher mortality compared with those with preserved functional ability.


Subject(s)
Frailty , Myocardial Infarction , Aged , Frail Elderly , Humans , Prognosis , Prospective Studies , Retrospective Studies
3.
Lakartidningen ; 1162019 Jun 11.
Article in Swedish | MEDLINE | ID: mdl-31192379

ABSTRACT

At the turn of the year 2018/19, a new ICD-10 code (E78.0A) will be introduced in Sweden for the hereditary blood lipid disorder familial hypercholesterolemia (FH). Patients with FH have a significantly increased risk of developing atherosclerotic disease, such as myocardial infarction before the age of 50. However, early diagnosis and start of treatment of FH can ameliorate the disease's negative long term effects. The Swedish National Board of Health and Welfare gave in its guidelines from 2015 a high priority to the work of identifying and diagnosing individuals with FH in the general population. The introduction of the ICD-10 code E78.0A for FH may, when properly used, be an effective tool in this work.


Subject(s)
Hyperlipoproteinemia Type II , Adolescent , Adult , Aged , Child , Cholesterol, LDL/blood , Humans , Hyperlipoproteinemia Type II/classification , Hyperlipoproteinemia Type II/diagnosis , Hyperlipoproteinemia Type II/genetics , Hyperlipoproteinemia Type II/therapy , International Classification of Diseases , Middle Aged , Sweden , Young Adult
4.
Scand Cardiovasc J ; 47 Suppl 62: 1-10, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23941732

ABSTRACT

OBJECTIVES: The Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) collects data to support the improvement of care for heart disease. DESIGN: SWEDEHEART collects on-line data from consecutive patients treated at any coronary care unit n = (74), followed for secondary prevention, undergoing any coronary angiography, percutaneous coronary intervention, percutaneous valve or cardiac surgery. The registry is governed by an independent steering committee, the software is developed by Uppsala Clinical Research Center and it is funded by The Swedish national health care provider independent of industry support. Approximately 80,000 patients per year enter the database which consists of more than 3 million patients. RESULTS: Base-line, procedural, complications and discharge data consists of several hundred variables. The data quality is secured by monitoring. Outcomes are validated by linkage to other registries such as the National Cause of Death Register, the National Patient Registry, and the National Registry of Drug prescriptions. Thanks to the unique social security number provided to all citizens follow-up is complete. The 2011 outcomes with special emphasis on patients more than 80 years of age are presented. CONCLUSION: SWEDEHEART is a unique complete national registry for heart disease.


Subject(s)
Cardiology Service, Hospital , Coronary Care Units , Heart Diseases/therapy , Outcome and Process Assessment, Health Care , Quality Improvement , Quality of Health Care , Registries , Adolescent , Adult , Aged , Aged, 80 and over , Cardiac Surgical Procedures , Cardiology Service, Hospital/standards , Child , Child, Preschool , Coronary Angiography , Coronary Care Units/standards , Female , Heart Diseases/diagnosis , Heart Diseases/mortality , Humans , Infant , Infant, Newborn , Male , Medical Record Linkage , Middle Aged , Outcome and Process Assessment, Health Care/standards , Percutaneous Coronary Intervention , Quality Improvement/standards , Quality of Health Care/standards , Secondary Prevention , Sweden/epidemiology , Time Factors , Treatment Outcome , Young Adult
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