ABSTRACT
As many as 12 patients with the trigeminal algic status, the most severe manifestation of a trigeminal neuralgia exacerbation, were examined. Along with the grave painful syndrome, the patients demonstrated marked vegetovascular disorders, macro- and microcirculatory abnormalities, and hemostatic disorders (the DIC syndrome). For intensive therapy of the condition the authors recommend the use of carbamazepine derivatives, GABA-containing drugs, neuroleptics, antihistamine agents, drugs that improve microcirculation, followed by transcutaneous electric stimulation, allowing the removal of the painful syndrome.
Subject(s)
Disseminated Intravascular Coagulation/etiology , Facial Pain/etiology , Ischemia/etiology , Trigeminal Nerve/blood supply , Trigeminal Neuralgia/complications , Aged , Combined Modality Therapy , Disseminated Intravascular Coagulation/therapy , Facial Pain/therapy , Female , Humans , Ischemia/therapy , Middle Aged , Trigeminal Neuralgia/physiopathology , Trigeminal Neuralgia/therapyABSTRACT
As many as 45 patients with multiple sclerosis were examined for rheological blood properties. As compared to controls, the group under examination manifested the rise of plasma viscosity, acceleration of red blood cell aggregation. 26.2% of patients demonstrated an appreciable increase of blood viscosity. It is assumed that these changes contribute to the deterioration of microcirculation and aggravate the demyelinating process. Correction of the rheological properties of the blood by plasmapheresis coupled with other methods of pathogenetic therapy turned out effective.
Subject(s)
Arm/blood supply , Blood Viscosity/physiology , Erythrocyte Aggregation/physiology , Ischemia/etiology , Leg/blood supply , Multiple Sclerosis/blood , Plasmapheresis , Adult , Dextrans/administration & dosage , Female , Humans , Ischemia/therapy , Male , Multiple Sclerosis/complicationsABSTRACT
The use of transcranial Doppler sonography (TDS) in combined ultrasound diagnosis was the first to allow a noninvasive assessment of cerebral circulation. Altogether 50 patients in acute stroke period were examined. The results obtained were verified at surgery, cerebral angiography or autopsy. Changes in the velocity of the blood flow, its reversal, different Doppler sonogram pattern appeared controversial for cerebral and subarachnoid haemorrhages caused by the occlusion of the internal carotid artery or other factors of encephalomalacia. TDS employment promotes the improvement in the diagnosis of the cause underlying the acute impairment of cerebral circulation and in the prognosis of cerebral coma. The findings are correlated with routine echo-pulsography and Doppler sonography.
Subject(s)
Carotid Artery Thrombosis/diagnosis , Cerebrovascular Disorders/diagnosis , Echoencephalography/methods , Subarachnoid Hemorrhage/diagnosis , Carotid Artery Thrombosis/complications , Carotid Artery Thrombosis/physiopathology , Cerebrovascular Circulation , Cerebrovascular Disorders/etiology , Cerebrovascular Disorders/physiopathology , Diagnosis, Differential , Echoencephalography/instrumentation , Humans , Subarachnoid Hemorrhage/complications , Subarachnoid Hemorrhage/physiopathologyABSTRACT
The authors describe the technical parameters and methodology of transcranial Doppler sonography as applied to studying the blood flow in vessels of the brain base. The results of the examination carried out in 25 healthy subjects have shown a high informative value of transcranial Doppler sonography in studying the circulation in the arterial and venous collectors. The new method is compared with the routine Doppler sonography and echopulsography.
