[Roentgenological and radiological examination of persons with an increased risk of lung cancer]. / Rentgenologicheskoe i radiologicheskoe obsledovanie lits s povyshennoi veroiatnost'iu zabolet' rakom legkogo.

The present system of the detection of lung cancer does not provide sufficient efficacy of mass screening. The paper is concerned with the results of the examination of organized population. The following methods were used: questionnaires, large picture frame fluorography, cytological examination of the sputum, radiopulmonography with 133Xe, the determination of carcinoembryonic antigen and thyroid hormones in the blood serum. Altogether two groups were examined: 787 practically healthy persons with a high risk of lung cancer and 193 patients with verified lung cancer. The results obtained were correlated in both groups using various methods. Mass screening should include the isolation of high risk groups and the differentiation of persons by a degree of disease probability. Persons with a high risk of this disease are subjected to regular examination using large picture frame fluorography and cytology of the sputum. Radiopulmonography should be performed as an adjuvant diagnostic procedure to examine persons from high risk groups in the presence of changes on the fluorograms and atypical cells in the sputum.

[Indicators of thyroid hormones and carcinoembryonic antigen in persons with a high risk of lung cancer]. / Pokazateli tireoidnykh gormonov i rakovo-émbrional'nogo antigena u lits s vysokoi veroiatnost'iu zabolet' rakom legkogo.

An attempt was made to study CEA and thyroid hormones in high risk groups as there is evidence of their change in lung cancer patients. A questionnaire to distinguish between 4 types of the probability of lung cancer development and a method of radioconcurrent analysis to study the concentration of CEA and thyroid hormones in the blood serum were used. A high risk group included 320 practically healthy persons, a control group 108 patients with verified lung cancer. The results of the study have shown that the concentration of CEA and thyroid hormones increases more often in persons of the high risk group with noncancerous diseases than in persons without pathological pulmonary changes. With an increase in the degree of probability the frequency of a high concentration of CEA and thyroid hormones grows. The older the persons with a high risk of lung cancer, the higher the frequency of concentration of the thyroid hormones. Studies of CEA and thyroid hormones can be used for dynamic observation of persons with a high risk of lung cancer.