Subject(s)
Contrast Media , Head and Neck Neoplasms/diagnosis , Iron , Oxides , Contrast Media/pharmacokinetics , Dextrans , Ferrosoferric Oxide , Humans , Iron/pharmacokinetics , Lymph Nodes/metabolism , Lymphatic Metastasis , Magnetic Resonance Imaging , Magnetite Nanoparticles , Oxides/pharmacokineticsSubject(s)
Cholangiopancreatography, Endoscopic Retrograde/methods , Contrast Media , Iohexol/analogs & derivatives , Triiodobenzoic Acids , Contrast Media/adverse effects , Contrast Media/pharmacology , Humans , Iohexol/adverse effects , Iohexol/pharmacology , Pancreatitis/chemically induced , Triiodobenzoic Acids/adverse effects , Triiodobenzoic Acids/pharmacologySubject(s)
Contrast Media , Hepatic Artery/diagnostic imaging , Hepatic Veins/diagnostic imaging , Liver Transplantation/diagnostic imaging , Polysaccharides , Budd-Chiari Syndrome/diagnostic imaging , Budd-Chiari Syndrome/etiology , Humans , Liver Transplantation/adverse effects , Perioperative Care , Ultrasonography, Doppler, ColorSubject(s)
Gadolinium DTPA , Magnetic Resonance Imaging/methods , Urography/methods , Contrast Media , HumansSubject(s)
Cholangiopancreatography, Endoscopic Retrograde , Contrast Media , Iohexol/analogs & derivatives , Animals , Contrast Media/administration & dosage , Contrast Media/adverse effects , Endoscopy , Humans , Iopamidol , Pancreas/drug effects , Pancreatitis/chemically induced , Risk Factors , Triiodobenzoic AcidsSubject(s)
Blood Coagulation Disorders/chemically induced , Contrast Media/adverse effects , Hemostasis/drug effects , Angioplasty, Balloon, Coronary , Animals , Blood Coagulation/drug effects , Blood Platelets/drug effects , Coronary Angiography , Coronary Disease/therapy , Erythrocyte Aggregation/drug effects , Humans , Thrombosis/chemically inducedSubject(s)
Contrast Media/toxicity , Kidney Diseases/chemically induced , Kidney/drug effects , Algorithms , Angiography , Animals , Aortography , Contrast Media/administration & dosage , Creatinine/blood , Diatrizoate/toxicity , Glomerular Filtration Rate/drug effects , Humans , Iohexol/toxicity , Kidney/diagnostic imaging , Kidney Diseases/blood , Purinergic P1 Receptor Antagonists , Receptors, Purinergic P1/drug effects , Risk Factors , UrographyABSTRACT
The investigation involved 22 reproductive and menopausal women (aged 30-48) with atypical endometrial hyperplasia. In addition to general clinical examination, all the patients underwent ultrasound scanning of the organs of the small pelvis, hysteroscopy and diagnostic curettage for morphological examination both before and after treatment. All tissue samples taken before and after treatment were assayed for cytoplasmic and plasma-membrane receptor levels and a number of biochemical parameters of plasma membranes. Hormone therapy with prolonged-release gestagen-based drugs pointed to changes which occurred in: (1) sex steroid reception at cytosol and plasma-membrane levels; (2) the lipids profile of plasma membranes, and (3) activity of membrane-related enzymes. Among the beneficial results of gestagen treatment was coming most of lipid profile parameters and plasma-membrane enzymes back to normal. However, a decrease in the progesterone reception level in target tissue after 3-6 month treatment may suggest a likelihood of development of tolerance to gestagen. The data also suggest that further research continue in this area of endometrial precancer.
Subject(s)
Endometrial Hyperplasia/diagnosis , Endometrial Hyperplasia/drug therapy , Endometrial Neoplasms/prevention & control , Progestins/therapeutic use , Adult , Cell Membrane/metabolism , Cytosol/metabolism , Drug Tolerance , Endometrial Hyperplasia/blood , Endometrial Hyperplasia/pathology , Female , Humans , Lipid Metabolism , Middle Aged , Receptors, Progesterone/metabolism , Treatment OutcomeABSTRACT
It was shown by the method of fluorescent probes that iodine-containing radiocontrast agents Triombrast > Omnipaque > Ultravist > Melitrast increase the content of intracellular Ca2+ in macrophages of the abdominal cavity of rats. Increase in the entry of Ca2+ from the external environment is the main factor of the change in the intracellular concentration of Ca2+ ions in the macrophages in interaction with radiocontrast agents.
